15 December 2020>: Clinical Research
Measurement of Cyclin D2 () Gene Promoter Methylation in Plasma and Peripheral Blood Mononuclear Cells and Alpha-Fetoprotein Levels in Patients with Hepatitis B Virus-Associated Hepatocellular Carcinoma
Yu Qian 1ABCDEF , Jing-Wen Wang 1BC , Yu-Fang 1BCD , Xiao-Dong Yuan 1B , Yu-Chen Fan 12ADF , Shuai Gao 12CDFG , Kai Wang 12ADEG*DOI: 10.12659/MSM.927444
Med Sci Monit 2020; 26:e927444
Table 3 CCND2 methylation levels in PBMCs and TNM stage from HCC patients.
Clinicopathological feature | Variable | Number of cases | Methylation | No methylation | Detection rate (%) |
---|---|---|---|---|---|
TNM stage | I | 48 | 16 | 32 | 33.33 |
II | 24 | 9 | 15 | 37.50 | |
III | 36 | 23 | 13 | 63.89 | |
IV | 10 | 7 | 3 | 70.00 | |
Total | 118 | 55 | 63 | 46.61 | |
TNM – tumor node metastasis; PBMCs – peripheral blood mononuclear cells. |