29 January 2021 : Database Analysis
Construction and Evaluation of a Risk Score Model for Autophagy-Related Genes in Esophageal Adenocarcinoma
Tianfu Xu1ABCDEF, Yamei Yuan2EFG*, Chenggong He3D, Kun Yang3DDOI: 10.12659/MSM.927850
Med Sci Monit 2021; 27:e927850
Table 2 Results of Gene Ontology (GO) enrichment analyses.
| A: Enrichment in phenotype: High. | |||
|---|---|---|---|
| Gene set name | NES | NOM P val | FDR q val |
| GO_REGULATION_OF_MITOTIC_SPINDLE_ASSEMBLY | 2.0 | 0.000 | 1.000 |
| GO_REGULATION_OF_SPINDLE_ASSEMBLY | 1.93 | 0.002 | 1.000 |
| GO_NEGATIVE_REGULATION_OF_DOUBLE_STRAND_BREAK_REPAIR_VIA_HOMOLOGOUS_RECOMBINATION | 1.89 | 0.004 | 1.000 |
| GO_MAGNESIUM_DEPENDENT_PROTEIN_SERINE_THREONINEPHOS_PHATASE_ACTIVITY | 1.87 | 0.006 | 1.000 |
| GO_POSITIVE_REGULATION_OF_ERYTHROCYTE_DIFFERENTIATION | 1.86 | 0.008 | 1.000 |
| NES – normalized enrichment score; NOM – nominal; FDR – false discovery rate. | |||
| B: Enrichment in phenotype: Low. | |||
| Gene set name | NES | NOM P val | FDR q val |
| GO_NEGATIVE_REGULATION_OF_VIRAL_RELEASE_FROM_HOST_CELL | −1.99 | 0.000 | 0.517 |
| GO_CYTOSOLIC_LARGE_RIBOSOMAL_SUBUNIT | −1.81 | 0.010 | 1.000 |
| GO_POSITIVE_REGULATION_OF_RECEPTOR_RECYCLING | −1.81 | 0.002 | 1.000 |
| GO_CYTOSOLIC_RIBOSOME | −1.79 | 0.028 | 1.000 |
| GO_RIBOSOMAL_SMALL_SUBUNIT_ASSEMBLY | −1.77 | 0.013 | 1.000 |
| NES – normalized enrichment score; NOM – nominal; FDR – false discovery rate. | |||