16 February 2021 : Animal Research
Effects of Diabetes Mellitus on Sperm Quality in the Db/Db Mouse Model and the Role of the FoxO1 Pathway
Jisheng Wang12ABDE, Binghao Bao12ABE, Junlong Feng12ABCE, Qi Zhao12BCF, Hengheng Dai12BDF, Fanchao Meng12BF, Sheng Deng12DF, Bin Wang2AG*, Haisong Li2AEDOI: 10.12659/MSM.928232
Med Sci Monit 2021; 27:e928232
Table 2 Top 10 key targets.
| Rank | Target name | Score |
|---|---|---|
| 1 | Insulin (INS) | 29 |
| 2 | Interleukin 6 (IL-6) | 26 |
| 3 | Tumor protein P53 (TP53) | 25 |
| 4 | Insulin like growth factor 1 (IGF1) | 24 |
| 4 | AKT serine/Threonine kinase 1 (AKT1) | 24 |
| 6 | Leptin (LEP) | 23 |
| 6 | Albumin (ALB) | 23 |
| 8 | Tumor necrosis factor (TNF) | 22 |
| 9 | HRas Proto-Oncogene, GTPase (HRAS) | 20 |
| 9 | Proopiomelanocortin (POMC) | 20 |