16 February 2021>: Animal Study
Effects of Diabetes Mellitus on Sperm Quality in the Db/Db Mouse Model and the Role of the FoxO1 Pathway
Jisheng Wang 12ABDE* , Binghao Bao 12ABE* , Junlong Feng 12ABCE* , Qi Zhao 12BCF* , Hengheng Dai 12BDF , Fanchao Meng 12BF , Sheng Deng 12DF , Bin Wang 2AG* , Haisong Li 2AE*DOI: 10.12659/MSM.928232
Med Sci Monit 2021; 27:e928232
Table 2 Top 10 key targets.
Rank | Target name | Score |
---|---|---|
1 | Insulin (INS) | 29 |
2 | Interleukin 6 (IL-6) | 26 |
3 | Tumor protein P53 (TP53) | 25 |
4 | Insulin like growth factor 1 (IGF1) | 24 |
4 | AKT serine/Threonine kinase 1 (AKT1) | 24 |
6 | Leptin (LEP) | 23 |
6 | Albumin (ALB) | 23 |
8 | Tumor necrosis factor (TNF) | 22 |
9 | HRas Proto-Oncogene, GTPase (HRAS) | 20 |
9 | Proopiomelanocortin (POMC) | 20 |