Comparison of Second- and Third-Generation Parathyroid Hormone Test Results in Patients with Chronic Kidney Disease

Magdalena Wójtowicz; Wiesław Piechota; Zofia Wańkowicz; Jerzy Smoszna; Stanisław Niemczyk

doi:10.12659/MSM.928301

24 December 2020 : Clinical Research

Comparison of Second- and Third-Generation Parathyroid Hormone Test Results in Patients with Chronic Kidney Disease

Magdalena Wójtowicz^1ABCDEF, Wiesław Piechota^1CDEF*, Zofia Wańkowicz^2DEF, Jerzy Smoszna^2DE, Stanisław Niemczyk^2DE

DOI: 10.12659/MSM.928301

Med Sci Monit 2020; 26:e928301

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Table 5 Correlations between intact parathyroid hormone and parathyroid hormone 1–84 concentrations and kidney function indices, calcium-phosphate metabolism parameters, and bone metabolism markers (Spearman method).

	iPTH
	Study group (n=205)
	Predialysis period (n=78)	Hemodialyzed (n=95)	Peritoneal dialysis (n=32)	Patients with CKD stages 3–5 and 5D (n=205)
Creatinine	0.6519^***	0.2154^*	0.0081	0.5325^***
eGFR	−0.6602^***	−0.1981	−0.0346	−0.5340^***
CKD-EPI creatinine-cystatin	−0.6713^***	−0.2061^*	0.0227	−0.5352^***
Urea	0.5195^***	0.1284	0.2872	0.4035^***
Cystatin C	0.6498^***	0.1632	0.0414	0.5172^***
Ca total	−0.4912^***	−0.2728^**	−0.1029	−0.4994^***
Ca ionized	−0.3790^***	−0.3043^**	−0.0317	−0.4325^***
Inorganic phosphate	0.2282^*	0.2664^**	0.4439^*	0.4352^***
Mg	0.0003	−0.0376	0.4316^*	−0.0156
ALP	0.3599^**	0.5331^***	0.0552	0.4663^***
BAP	0.4505^***	0.6097^***	0.1746	0.5545^***
Osteocalcin	0.7054^***	0.6271^***	0.4028^*	0.7270^***
β-CrossLaps	0.6595^***	0.7042^***	0.6309^***	0.7596^***



Creatinine	0.6253^***	0.1693	−0.1037	0.4853^***
eGFR	−0.6333^***	−0.1599	0.0911	−0.4865^***
CKD-EPI creatinine-cystatin	−0.6436^***	−0.1612	0.1311	−0.4858^***
Urea	0.4846^***	0.1114	0.2852	0.3833^***
Cystatin C	0.6213^***	0.1129	−0.0282	0.4680^***
Ca total	−0.4805^***	−0.2846^**	−0.1177	−0.4900^***
Ca ionized	−0.3666^***	−0.3062^**	−0.0760	−0.4340^***
Inorganic phosphate	0.2147	0.2245^*	0.3759^*	0.3979^***
Mg	0.0001	−0.0479	0.3996^*	−0.0106
ALP	0.3609^**	0.5459^***	0.1161	0.4760^***
BAP	0.4627^***	0.6175^***	0.2496	0.5652^***
Osteocalcin	0.7036^***	0.6107^***	0.4262^*	0.7115^***
β-CrossLaps	0.6542^***	0.6888^***	0.6355^***	0.7416^***
^* p ^ p ^* p

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Comparison of Second- and Third-Generation Parathyroid Hormone Test Results in Patients with Chronic Kidney Disease

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