20 January 2021 : Meta-Analysis
Association Between Mitochondrial DNA Copy Number and Head and Neck Squamous Cell Carcinoma: A Systematic Review and Dose-Response Meta-Analysis
Zhu Zhu1ABCDEF, Yixiu Liu2B, Didi Wu1C, Hongpeng Wang2ABCDEF*DOI: 10.12659/MSM.928327
Med Sci Monit 2021; 27:e928327
Supplementary Table 1 Supplementary information of included studies.
| Study | Age (years) | Gender (% Male) | Smoking (% ever) | Drinking (% ever) | Categorization | Number | |
|---|---|---|---|---|---|---|---|
| Case/control | Case/control | Case/control | Case | Control | |||
| Kim 2004 | 62.4/38.8 | – | – | – | No | ||
| Jiang 2005 | 56.8/61.8 | 71 (75.5)/413 (63.3) | 52 (79.1)/405 (62.0) | – | No | ||
| Mondal 2013 | 58/56 | 98 (79.0)/101 (72.1) | 89 (71.7)/75 (53.4) | – | By quartile | ||
| ≤0.1 | 58 | 43 | |||||
| >0.1–1 | 35 | 42 | |||||
| >1–10 | 19 | 29 | |||||
| >10 | 12 | 26 | |||||
| Cheau-Feng Lin 2014 | 56±11.9/− | 75 (100)/− | 61 (81.3)/− | 50 (66.7)/− | No | ||
| Dang 2014 | 60.75±9.64/− | 197 (96.6)/− | 141 (69.1)/− | – | No | ||
| Ghosh 2014 | – | 49 (76.6)/79 (79.0) | 43 (67.2)/27 (27.0) | 44 (68.8) | By quartile | ||
| /49 (49.0) | ≤0.2 | 31 | 29 | ||||
| >0.2–2 | 15 | 27 | |||||
| >2–12 | 11 | 25 | |||||
| >12 | 7 | 19 | |||||
| He 2014 | 57.3±12.4/58.5±11.4 | 87 (60.8)/215 (60.2) | 83 (58.0)/175 (49.0) | 85 (59.4) | By median | ||
| /108 (30.3) | 56 | 186 | |||||
| ≥1.08 | 87 | 171 | |||||
| Wang 2018 | 61.07±10.88/59.62±9.35 | 357 (62.6)/374 (62.7) | 258 (45.3)/253 (42.4) | 252 (44.2) | By quartile | ||
| /192 (32.2) | 165 | 150 | |||||
| 1.93–3.50 | 89 | 149 | |||||
| 3.50–11.22 | 119 | 149 | |||||
| >11.22 | 197 | 149 | |||||