03 February 2021 : Clinical Research
Efficacy of Beraprost Sodium Combined with Sildenafil and Its Effects on Vascular Endothelial Function and Inflammation in Patients Experiencing Left Heart Failure Complicated with Pulmonary Arterial Hypertension
Daoyuan Sun1ABE, Wenlan Yang2BDE, Zhenwei Wang3CDF, Beilan Gao4ACG*DOI: 10.12659/MSM.928413
Med Sci Monit 2021; 27:e928413
Table 2 Comparisons of echocardiographic parameters before treatment and at 3 months after treatment between the 2 groups (χ̆±s). Observation group: beraprost sodium combined with sildenafil; control group: beraprost sodium only.
| LVEF (%) | CO (L/min) | SV (mL/b) | ||
|---|---|---|---|---|
| Observation group | Before intervention | 41.3±1.6 | 2.8±0.2 | 42.1±4.3 |
| After intervention | 63.3±3.8 | 5.1±0.4 | 65.9±5.9 | |
| Control group | Before intervention | 41.4±1.6 | 2.8±0.2 | 42.0±4.4 |
| After intervention | 53.8±2.3 | 4.6±0.3 | 59.3±5.1 | |
| t | – | 32.213 | 56.288 | 16.286 |
| – | <0.001 | <0.001 | <0.001 | |
| t | – | 16.704 | 29.698 | 10.610 |
| – | <0.001 | <0.001 | <0.001 | |
| t | – | 0.226 | 0.000 | 0.103 |
| – | 0.821 | 1.000 | 0.918 | |
| t | – | 19.222 | 22.804 | 6.163 |
| – | <0.001 | <0.001 | <0.001 | |
| and : before intervention vs after intervention in the observation group; and : before intervention vs after intervention in the control group; and : observation group vs control group before intervention; and : observation group vs control group after intervention. LVEF – left ventricular ejection fraction; CO – cardiac output; SV – stroke volume. | ||||