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03 February 2021 : Clinical Research  

Efficacy of Beraprost Sodium Combined with Sildenafil and Its Effects on Vascular Endothelial Function and Inflammation in Patients Experiencing Left Heart Failure Complicated with Pulmonary Arterial Hypertension

Daoyuan Sun1ABE, Wenlan Yang2BDE, Zhenwei Wang3CDF, Beilan Gao4ACG*

DOI: 10.12659/MSM.928413

Med Sci Monit 2021; 27:e928413

Table 3 Comparisons of vascular endothelial function-related indicators at 3 months after treatment between the 2 groups (χ̆±s). Observation group: beraprost sodium combined with sildenafil; control group: beraprost sodium only.

Nitric oxide (μmol/L)Vascular endothelin-1 (ng/L)
Observation group59.9±10.527.6±2.5
Control group37.4±1.460.1±5.3
t13.43435.076
<0.001<0.001

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750