15 February 2021 : Clinical Research
Polymorphisms in IRF5 and TYK2 Genes Are Associated with Rheumatoid Arthritis in a Chinese Han Population
Yuqin Peng1BC, Bingqian Chen1BCD, Xiaowen Sheng1DE, Yufeng Qian1AEG*DOI: 10.12659/MSM.928455
Med Sci Monit 2021; 27:e928455
Table 1 Clinical Characteristics of patients with rheumatoid arthritis and healthy controls (n=578).
| Clinical features | Case | Control | p |
|---|---|---|---|
| Male/Female | 51/527 | 55/523 | >0.05 |
| Age (years) | 44.7±12.3 | 45.6±12.8 | >0.05 |
| ESR (mm/h) | 35.1±14.2 | 12.1±8.5 | <0.05 |
| CRP (mg/l) | 26.5±11.2 | 4.7±12.5 | <0.05 |
| HLA-B27+, % | 1/578 (0.17%) | 0/578 (0%) | >0.05 |
| ANA+, % | 102/578 (17.6%) | 0/578 (0%) | <0.05 |
| RF+, % | 224/578 (387%) | 0/578 (0%) | <0.05 |
| ANA – antinuclear antibodies; ESR – erythrocyte sedimentation rate; CRP – C-reactive protein; RF – rheumatoid factor. ‘+’ – positive. | |||