Functional Analysis of Estrogen Receptor 1 in Diabetic Wound Healing: A Knockdown Cell-Based and Bioinformatic Study

18 December 2020: Database Analysis

Sha Qi ^ABC , Qiong Han ^BC , Danmou Xing ^D , Long Qian ^CE , Xiang Yu ^E , Dong Ren ^F , Huan Wang ^E , Quan Chen ^ABFG*

DOI: 10.12659/MSM.928788

Med Sci Monit 2020; 26:e928788

Table 3 The upregulated and downregulated differentially expressed genes (DEGs) in molecular function.

Term	Function	Count	P-value

GO: 0005085	Guanyl-nucleotide exchange factor activity	17	3.1E-3
GO: 0098772	Molecular function regulator	50	4.2E-3
GO: 0005088	Ras guanyl-nucleotide exchange factor activity	13	8.8E-3
GO: 0052745	Inositol phosphate phosphatase activity	4	9.9E-3
GO: 0030170	Pyridoxal phosphate binding	6	1.2E-2

GO: 0044822	Poly(A) RNA binding	50	7.8E-6
GO: 0000166	Nucleotide binding	80	3.4E-5
GO: 1901265	Nucleoside phosphate binding	80	3.4E-5
GO: 0036094	Small molecule binding	82	1.4E-4
GO: 0097367	Carbohydrate derivative binding	73	2.0E-4