18 December 2020 : Database Analysis
Functional Analysis of Estrogen Receptor 1 in Diabetic Wound Healing: A Knockdown Cell-Based and Bioinformatic Study
Sha Qi1ABC, Qiong Han1BC, Danmou Xing1D, Long Qian1CE, Xiang Yu1E, Dong Ren1F, Huan Wang1E, Quan Chen1ABFG*DOI: 10.12659/MSM.928788
Med Sci Monit 2020; 26:e928788
Table 4 The Kyoto Encyclopedia of Genes and Genomes analysis of upregulated and downregulated differentially expressed genes (DEGs).
| Term | Function | Count | P-value |
|---|---|---|---|
| hsa00600 | Sphingolipid metabolism pathway | 6 | 5.3E-3 |
| hsa04915 | Estrogen signaling pathway | 8 | 1.0E-2 |
| hsa04512 | ECM-receptor interaction pathway | 7 | 1.9E-2 |
| hsa04010 | MAPK signaling pathway | 13 | 2.0E-2 |
| hsa04151 | PI3K-Akt signaling pathway | 16 | 2.0E-2 |
| hsa04390 | Hippo signaling pathway | 11 | 6.1E-4 |
| hsa04350 | TGF-beta signaling pathway | 6 | 2.2E-2 |
| hsa03015 | mRNA surveillance pathway | 6 | 3.0E-2 |
| hsa04152 | AMPK signaling pathway | 7 | 3.1E-2 |
| hsa04360 | Axon guidance pathway | 7 | 3.5E-2 |