18 December 2020: Database Analysis
Functional Analysis of Estrogen Receptor 1 in Diabetic Wound Healing: A Knockdown Cell-Based and Bioinformatic Study
Sha Qi ABC , Qiong Han BC , Danmou Xing D , Long Qian CE , Xiang Yu E , Dong Ren F , Huan Wang E , Quan Chen ABFG*DOI: 10.12659/MSM.928788
Med Sci Monit 2020; 26:e928788
Table 5 The top 10 genes by degree of association between one node and other nodes.
| Gene ID | Gene name | Degree | Betweenness | Closeness |
|---|---|---|---|---|
| JUN | Jun proto-oncogene, AP-1 transcription factor subunit | 48 | 51655 | 5.18E-4 |
| ESR1 | Estrogen receptor 1 | 36 | 31527 | 5.02E-4 |
| CD44 | CD44 molecule | 36 | 27941 | 4.89E-4 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily A, member 4 | 34 | 29067 | 4.87E-4 |
| MMP2 | Matrix metallopeptidase 2 | 34 | 18562 | 4.85E-4 |
| BMP4 | Bone morphogenetic protein 4 | 32 | 14246 | 4.63E-4 |
| GSK3B | Glycogen synthase kinase 3 beta | 29 | 22274 | 4.86E-4 |
| WDR5 | WD repeat domain 5 | 29 | 21188 | 4.67E-4 |
| PTK2 | Protein tyrosine kinase 2 | 29 | 22879 | 4.63E-4 |
| PTGS2 | Prostaglandin-endoperoxide synthase 2 | 29 | 18796 | 4.76E-4 |