18 December 2020>: Database Analysis
Functional Analysis of Estrogen Receptor 1 in Diabetic Wound Healing: A Knockdown Cell-Based and Bioinformatic Study
Sha Qi ABC , Qiong Han BC , Danmou Xing D , Long Qian CE , Xiang Yu E , Dong Ren F , Huan Wang E , Quan Chen ABFG*DOI: 10.12659/MSM.928788
Med Sci Monit 2020; 26:e928788
Table 6 Functional and pathway enrichment analyses of the genes in the protein–protein (PPI) network.
Term | Name | Count | P-value |
---|---|---|---|
GO: 0045597 | Positive regulation of cell differentiation | 66 | 1.7E-7 |
GO: 0072358 | Cardiovascular system development | 68 | 2.4E-6 |
GO: 0072359 | Circulatory system development | 68 | 2.4E-6 |
GO: 0005654 | Nucleoplasm | 153 | 3.1E-3 |
GO: 0005578 | Proteinaceous extracellular matrix | 27 | 4.6E-3 |
GO: 0097517 | Contractile actin filament bundle | 8 | 6.7E-3 |
GO: 0098772 | Molecular function regulator | 84 | 6.7E-5 |
GO: 0008134 | Transcription factor binding | 39 | 1.2E-4 |
GO: 0005539 | Glycosaminoglycan binding | 20 | 5.2E-4 |
hsa: 05205 | Proteoglycans in cancer pathway | 17 | 4.8E-3 |
hsa: 05200 | Pathways in cancer | 27 | 5.4E-3 |
hsa: 04390 | Hippo signaling pathway | 14 | 5.8E-3 |