Prognostic Factors for Survival in Patients with Malignant Giant Cell Tumor of Bone: A Risk Nomogram Analysis Based on the Population

Xiaolong Zhu; Runzhi Huang; Peng Hu; Penghui Yan; Suna Zhai; Jie Zhang; Junwei Zhuang; Huabin Yin; Tong Meng; Daoke Yang; Zongqiang Huang

doi:10.12659/MSM.929154

17 February 2021 : Database Analysis

Prognostic Factors for Survival in Patients with Malignant Giant Cell Tumor of Bone: A Risk Nomogram Analysis Based on the Population

Xiaolong Zhu^1BCDEF, Runzhi Huang^12ABCDEF, Peng Hu^1E, Penghui Yan^1ABCDEF, Suna Zhai^3D, Jie Zhang^2AE, Junwei Zhuang^1F, Huabin Yin^4E, Tong Meng^4AF*, Daoke Yang^3F, Zongqiang Huang^1AG

DOI: 10.12659/MSM.929154

Med Sci Monit 2021; 27:e929154

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Table 1 Results of single factor analysis and random forest.

Variables	Overall survival (OS)			Cancer specific survival (CSS)
Variables	P value of non-parametric test	P value of Kaplan-Meier analysis	MDG	P value of non-parametric test	P value of Kaplan-Meier analysis	MDG
Age	<0.001^*	<0.001^*	21.381	<0.001^*	<0.001^*	8.839
Race recode	0.387	0.190	5.088	0.077	0.037^*	4.569
Gender	0.017^*	0.023^*	5.232	0.565	0.540	3.368
Primary site	<0.001^*	<0.001^*	8.435	<0.001^*	<0.001^*	7.345
ICD-O-3.histology	0.001^*	0.002^*	6.908	0.009^*	0.037^*	2.926
Surgery information	0.144	0.012^*	3.630	0.040^*	0.007^*	2.649
Radiation recode	0.017^*	0.010^*	3.269	<0.001^*	<0.001^*	3.409
Chemotherapy recode	<0.001^*	<0.001^*	7.740	<0.001^*	<0.001^*	6.832
Historic stage	<0.001^*	<0.001^*	10.478	<0.001^*	<0.001^*	11.243
Marital status	0.064	0.120	5.054	0.005^*	0.009^*	3.151
9 grade education	0.742	0.350	4.447	0.913	0.720	2.521
High school education	0.355	0.730	3.772	0.634	0.750	2.395
At least bachelor degree	0.692	0.920	2.420	0.874	0.750	1.790
Median family income	0.596	0.290	3.469	0.565	0.440	2.191
Families below poverty	0.647	0.260	2.836	0.335	0.250	2.040
Unemployed	0.948	0.790	3.976	0.457	0.390	2.494
White collar	0.400	0.550	2.958	0.554	0.570	2.155
Categorical variables were compared by using the Pearson Chi-square test. Continuous variables in normal distribution and homogeneity of variance were compared by using the two-sample t test. OS – overall survival; CSS – cause-specific survival; MDG – Mean Decrease Gini. ^* P

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Prognostic Factors for Survival in Patients with Malignant Giant Cell Tumor of Bone: A Risk Nomogram Analysis Based on the Population

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