Decreased HLF Expression Predicts Poor Survival in Lung Adenocarcinoma

Zaiyan Wang; Xiaoning Li; Hao Chen; Li Han; Xiaobin Ji; Qiubo Wang; Li Wei; Yafang Miao; Jing Wang; Jianfeng Mao; Zeming Zhang

doi:10.12659/MSM.929333

12 May 2021 : Database Analysis

Decreased HLF Expression Predicts Poor Survival in Lung Adenocarcinoma

Zaiyan Wang^1BE, Xiaoning Li^1BE, Hao Chen^1CF, Li Han^1CD, Xiaobin Ji^1BD, Qiubo Wang^1DF, Li Wei^1BF, Yafang Miao^1CF, Jing Wang^1F, Jianfeng Mao^1F, Zeming Zhang^1AG*

DOI: 10.12659/MSM.929333

Med Sci Monit 2021; 27:e929333

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Table 2 Functional and pathway enrichment analysis of the DEGs.

Term	Name	Count	P value

GO: 0007155	Cell adhesion	17	9.7E-6
GO: 0001763	Morphogenesis of a branching structure	4	4.8E-5
GO: 0001525	Angiogenesis	10	3.2E-4

GO: 0005515	Protein binding	94	1.1E-2
GO: 0008289	Lipid binding	6	1.2E-2
GO: 0001077	Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	7	1.9E-2

GO: 0005887	Integral component of plasma membrane	29	7.7E-5
GO: 0045121	Membrane raft	10	1.2E-4
GO: 0005886	Plasma membrane	59	1.9E-4

hsa04512	ECM-receptor interaction	6	2.5E-3
Hsa04974	Protein digestion and absorption	5	1.5E-2
hsa04360	Axon guidance	5	4.9E-2
ECM – extracellular membrane; KEGG – Kyoto Encyclopedia of Genes and Genomes. When more than 3 enriched terms were identified in each category, the top 3 terms were selected according to value.

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Decreased HLF Expression Predicts Poor Survival in Lung Adenocarcinoma

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