Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

18 April 2021: Animal Study

Left Ventricular Impaired Relaxation and Interstitial Myocarditis Identified in Sepsis-Associated Cardiac Dysfunction: Use of a Rodent Model

David J. Sturgess 1ABCDEFG* , Shannon Morrison 1BCDE , Brian Haluska 2BCD , Glenda C. Gobe 23BCDEG , Mark A. Jones 4ACDE , Sonia Volante 1BE , Bala Venkatesh 2ACDEG

DOI: 10.12659/MSM.929512

Med Sci Monit 2021; 27:e929512

Table 1 Final assessment of function: LPS model.

MAP (mmHg)124.29±20.1681.86±31.670.020
Heart rate (bpm)421.1±47451.2±46.40.20
LVIDs (mm)0.39±0.120.61±0.190.13
LVIDd (mm)0.67±0.110.26±0.140.70
FS (%)43.3±9.558.8±17.20.085
VTI (cm)9±65.27±1.730.093
Vpeak (m/s)4.17±0.741.35±1.730.17
E (m/s)0.83±0.240.79±0.130.65
e′ (m/s)0.09±0.020.06±0.020.008
Analysis of covariance (ANCOVA) performed to compare groups at final time point with adjustment for baseline measurements. LV end-systolic (LVIDs) and end-diastolic (LVIDd) internal dimension; FS – fractional shortening; VTI – velocity time integral; Vpeak – outflow peak velocity; Peak early (E) diastolic transmitral velocity; Peak early (e′) diastolic septal mitral annulus velocity; E/e′ – ratio of E to e′.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750