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18 April 2021: Animal Study

Left Ventricular Impaired Relaxation and Interstitial Myocarditis Identified in Sepsis-Associated Cardiac Dysfunction: Use of a Rodent Model

David J. Sturgess 1ABCDEFG* , Shannon Morrison 1BCDE , Brian Haluska 2BCD , Glenda C. Gobe 23BCDEG , Mark A. Jones 4ACDE , Sonia Volante 1BE , Bala Venkatesh 2ACDEG

DOI: 10.12659/MSM.929512

Med Sci Monit 2021; 27:e929512

Table 2 Histopathology results for LPS model LV myocardium with HE staining.

GroupMarked hydropic changeMild hydropic changeModerate hydropic changeTotal
Control (no.)0437
Endotoxin (no.)5027
Marked hydropic change was observed in five out of seven endotoxic animals, but was not present in any control animals, (P=0.015; Fisher exact). HE – hematoxylin and eosin staining.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750