Elevated Plasma Angiopoietinlike Protein 5 (ANGPTL5) Is More Positively Associated with Glucose Metabolism Disorders in Patients with Metabolic Syndrome

Chang Liu; Xin Yi; Yongnan Lyu; Wei Ren; Yi Zhou; Gaoke Feng; Weiguo Wan; Xue-jun Jiang

doi:10.12659/MSM.929626

24 January 2021 : Clinical Research

Elevated Plasma Angiopoietinlike Protein 5 (ANGPTL5) Is More Positively Associated with Glucose Metabolism Disorders in Patients with Metabolic Syndrome

Chang Liu^123ABCD, Xin Yi^123AEG, Yongnan Lyu^123CF, Wei Ren^4CD, Yi Zhou^123BF, Gaoke Feng^123E, Weiguo Wan^123B, Xue-jun Jiang^123AEG*

DOI: 10.12659/MSM.929626

Med Sci Monit 2021; 27:e929626

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Table 2 Correlations of plasma angiopoietinlike protein 5 (ANGPTL5) with laboratory parameters in patients with metabolic syndrome (MS).

Variables	Non-MS		MS		Total
Variables	r1	P1	r2	P2	r3	P3
Age	0.160	0.186	0.172	0.186	0.233	0.006
BMI	0.098	0.419	0.194	0.111	0.602	<0.001
Waist circumference	−0.062	0.610	0.252	0.037	0.591	<0.001
WHR	0.155	0.200	0.077	0.532	0.563	<0.001
SBP	0.070	0.564	−0.078	0.523	0.256	0.002
DBP	−0.084	0.489	−0.016	0.896	−0.120	0.159
FPG	0.176	0.145	0.364	0.002	0.690	<0.001
FINS	0.075	0.535	0.634	<0.001	0.470	<0.001
HbA1c	−0.042	0.729	0.189	0.119	0.590	<0.001
TC	0.065	0.593	−0.011	0.929	0.325	<0.001
TG	−0.033	0.787	0.038	0.758	0.454	<0.001
HDL-C	−0.223	0.064	−0.087	0.476	−0.257	0.002
LDL-C	0.100	0.412	0.012	0.925	0.419	<0.001
hs-CRP	0.132	0.275	−0.009	0.942	0.210	0.014
BUN	0.108	0.374	−0.173	0.156	0.066	0.438
CREA	−0.103	0.396	−0.030	0.806	−0.031	0.719
URIC	−0.105	0.386	−0.051	0.674	0.207	0.014
TBIL	−0.073	0.549	−0.097	0.426	−0.025	0.770
DBIL	−0.063	0.607	−0.025	0.840	−0.104	0.225
IBIL	−0.091	0.452	−0.126	0.304	0.019	0.825
AST	0.249	0.038	−0.049	0.687	0.111	0.192
ALT	−0.072	0.551	−0.020	0.868	−0.024	0.783
GGT	−0.005	0.970	−0.149	0.222	0.000	0.996
HOMA-IR	0.144	0.235	0.635	<0.001	0.685	<0.001
HOMA-β	−0.127	0.294	−0.052	0.673	−0.553	<0.001
Pearson correlation analysis was used for data conforming to normal distribution, and Spearman correlation analysis was used for data not conforming to normal distribution. r and P represent correlation coefficient and value in the non-MS group; r and P represent correlation coefficient and value in the MS group; r and P represent correlation coefficient and value in the total population.

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Elevated Plasma Angiopoietinlike Protein 5 (ANGPTL5) Is More Positively Associated with Glucose Metabolism Disorders in Patients with Metabolic Syndrome

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