11 May 2021: Clinical Research
Efficacy and Safety of Sea Salt-Derived Physiological Saline Nasal Spray as Add-On Therapy in Patients with Acute Upper Respiratory Infection: A Multicenter Retrospective Cohort Study
Min Jiang 1ABDEF , Junwen Chen 2B , Yuanhua Ding 3B , Chenxi Gan 4BDF , Ya Hou 5CD , Junge Lei 1BE , Mengzhi Wan 1B , Xing Li 1B , Zuke Xiao 1ACG*DOI: 10.12659/MSM.929714
Med Sci Monit 2021; 27:e929714
Table 1 Baseline patient features and posttreatment vital signs in the 2 groups.
| Seawater group | Control group | P | |
|---|---|---|---|
| Age (years) | 40.3±13.3 (20–65) | 39.2±13.1 (20–64) | 0.611 |
| Sex | 0.725 | ||
| Female | 31 | 29 | |
| Male | 41 | 43 | |
| Body temperature (°C) | 36.6±0.3 (36.1–38.5) | 36.6±0.3 (36.0–37.3) | 0.437 |
| Pulse rate (beats/min) | 77±13 (58–95) | 79±5 (68–90) | 0.406 |
| Respiratory rate (breaths/min) | 21±11 (15–24) | 19±1 (15–21) | 0.209 |
| Systolic pressure (mmHg) | 122±8 (96–140) | 120±9 (95–139) | 0.147 |
| Diastolic pressure (mmHg) | 76±6 (60–90) | 75±8 (60–92) | 0.241 |
| Body temperature (°C) | 36.5±0.3 (36.0–37.0) | 36.4±0.2 (36.4–37.1) | 0.333 |
| Pulse rate (beats/min) | 77±9 (69–90) | 77±8 (68–89) | 0.290 |
| Respiratory rate (breaths/min) | 19±2 (15–22) | 19±2 (15–21) | 0.446 |
| Systolic pressure (mmHg) | 122±8 (96–140) | 119±8 (95–139) | 0.301 |
| Diastolic pressure (mmHg) | 74±5 (60–86) | 75±6 (60–90) | 0.403 |
| All continuous data are shown as mean±standard deviation (range). | |||