Predicting the Risk of Acute Kidney Injury in Patients After Percutaneous Coronary Intervention (PCI) or Cardiopulmonary Bypass (CPB) Surgery: Development and Assessment of a Nomogram Prediction Model

Yi Du; Xiu-Zhe Wang; Wei-Dong Wu; Hai-Peng Shi; Xiao-Jing Yang; Wen-Jing Wu; Shu-Xian Chen

doi:10.12659/MSM.929791

25 April 2021 : Clinical Research

Predicting the Risk of Acute Kidney Injury in Patients After Percutaneous Coronary Intervention (PCI) or Cardiopulmonary Bypass (CPB) Surgery: Development and Assessment of a Nomogram Prediction Model

Yi Du^1ABCDEFG, Xiu-Zhe Wang^1ABFG, Wei-Dong Wu^1ABCDE*, Hai-Peng Shi^1ABC, Xiao-Jing Yang^1CD, Wen-Jing Wu^1BC, Shu-Xian Chen^1EF

DOI: 10.12659/MSM.929791

Med Sci Monit 2021; 27:e929791

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Table 2 Univariate and multivariate logistic regression.

Variable	Univariate analysis		Multivariate analysis
Variable	OR (95% CI)	P value	OR (95% CI)	P value
Operation, CPB	0.244 (0.134–0.444)	<0.001	0.094 (0.032–0.279)	<0.001
Age (year)	1.057 (1.031–1.084)	<0.001	1.102 (1.055–1.151)	<0.001
Hypertension	0.964 (0.539–1.721)	0.9	NA
Diabetes	0.787 (0.371–1.666)	0.531	NA
Hypercholesterolemia	0.573 (0.321–1.022)	0.059	NA
Cerebral vascular accident	1.745 (0.589–5.167)	0.315	NA
Chronic obstructive pulmonary diease	0.804 (0.092–7.013)	0.843	NA
Congestive heart failure	2.000 (1.112–3.594)	0.021	2.605 (1.004–6.758)	0.049
Betablockers	0.785 (0.410–1.503)	0.465	NA
Angiotensinaldosterone system antagonists	0.568 (0.294–1.097)	0.092	NA
Estimated glomerular filtration rate	1.224 (0.869–1.723)	0.247	NA
BMI, ≥26.7(kg/m)	0.247 (0.136–0.451)	<0.001	0.339 (0.134–0.857)	0.022
Heart rate, ≥85/min	3.252 (1.799–5.880)	<0.001	2.929 (1.135–7.558)	0.026
WBC count, ≥12.9×10/L	4.103 (2.251–7.477)	<0.001	2.676 (1.045–6.854)	0.04
Platelet count, ≥174×10/L	0.117 (0.050–0.276)	<0.001	0.061 (0.013–0.296)	<0.001
Serum creatinine, ≥0.67 mg/dL	2.295 (0.780–6.749)	0.131	NA
Hemoglobin, ≥13.3 g/dL	0.191 (0.103–0.355)	<0.001	0.226 (0.089–0.574)	0.002
Hemoglobin A1c, ≥4.39%	2.593 (0.762–8.830)	0.127	NA
Uric acid, ≥7.532 mg/dL	3.148 (1.716–5.777)	<0.001	3.449 (1.213–9.806)	0.02
PI kidney cortex, ≥14.3 dB	0.200 (0.091–0.441)	<0.001	0.170 (0.050–0.581)	0.005
PI Kidney with mass, ≥11.47 dB	0.137 (0.071–0.263)	<0.001	0.149 (0.057–0.392)	<0.001
CPB – cardiopulmonary bypass; PI – peak intensity; WBC – white blood cells.

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Predicting the Risk of Acute Kidney Injury in Patients After Percutaneous Coronary Intervention (PCI) or Cardiopulmonary Bypass (CPB) Surgery: Development and Assessment of a Nomogram Prediction Model

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