21 June 2021 : Clinical Research
Association of Blood Pressure, White Matter Lesions, and Regional Cerebral Blood Flow
Dong Zhang1ABCDEF*, Jianyu Zhang1CEF, Bo Zhang2ABD, Jin Zhang1BDE, Mingli He1ABDEGDOI: 10.12659/MSM.929958
Med Sci Monit 2021; 27:e929958
Table 2 Logistics regression analysis of Fazekas grades and various factors.
| Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
| OR (95% CI) | P value | OR(95%CI) | P value | |
| Age | 1.102 (1.050–1.157) | <0.001 | 1.089 (1.034–1.147) | 0.001 |
| BMI | 0.891 (0.811–0.979) | 0.016 | 0.889 (0.792–0.997) | 0.045 |
| 24hMSBP | 1.099 (1.052–1.149) | <0.001 | 1.085 (1.029–1.145) | 0.003 |
| 24hMDBP | 1.053 (1.001–1.107) | 0.045 | 1.075 (1.006–1.147) | 0.031 |
| MDSBP | 1.067 (1.026–1.110) | 0.001 | 1.066 (1.021–1.112) | 0.004 |
| MNSBP | 1.110 (1.063–1.159) | <0.001 | 1.112 (1.059–1.169) | <0.001 |
| MDDBP | 1.027 (0.978–1.077) | 0.285 | 1.055 (0.998–1.115) | 0.059 |
| MNDBP | 1.075 (1.025–1.127) | 0.003 | 1.087 (1.030–1.147) | 0.002 |
| SBPDNR | 0.822 (0.753–0.897) | <0.001 | 0.801 (0.711–0.902) | <0.001 |
| DBPDNR | 0.906 (0.854–0.961) | 0.001 | 0.876 (0.807–0.950) | 0.001 |
| MSCBF (F3) | 1.000 | – | 1.000 | – |
| F2 | 1.338 (1.158–1.545) | <0.001 | 1.433 (1.186–1.732) | <0.001 |
| F1 | 1.654 (1.393–1.963) | <0.001 | 1.812 (1.456–2.254) | <0.001 |
| F0 | 1.799 (1.504–2.150) | <0.001 | 1.976 (1.576–2.477) | <0.001 |
| MPCBF (F3) | 1.000 | – | 1.000 | – |
| F2 | 1.313 (1.133–1.522) | <0.001 | 1.352 (1.129–1.618) | 0.001 |
| F1 | 1.757 (1.447–2.133) | <0.001 | 1.877 (1.486–2.372) | <0.001 |
| F0 | 1.900 (1.556–2.319) | <0.001 | 2.034 (1.602–2.583) | <0.001 |
| MDSBP – daytime mean systolic blood pressure; MNSBP – mean systolic blood pressure at night; MDDBP – daytime mean diastolic blood pressure; MNDBP – mean diastolic pressure at night; 24hSBP – 24-hour mean systolic blood pressure; 24hDBP – 24-hour mean diastolic blood pressure; SBPDNR – systolic blood pressure ratio between day and night; DBPDNR – diastolic blood pressure day/night ratio; MSCBF: bilateral mean subcortical local cerebral blood flow; MPCBF – bilateral mean paraventricular cerebral blood flow; F – Fazekas grade. | ||||