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10 August 2021: Clinical Research

A Novel Substrate-Inspired Fluorescence-Based Albumin Detection Improves Assessment of Clinical Outcomes in Hemodialysis Patients Receiving a Nursing Nutrition Intervention

Lei You ABCE* , Xia Wang BDEG* , Wenhong Wang DEF*

DOI: 10.12659/MSM.930257

Med Sci Monit 2021; 27:e930257

Table 1 Clinical baseline characteristics between the 2 groups.

ParametersIG, n=35CG, n=33P values
Age48.9±10.747.45±11.30.681
Male/Female20/1520/130.772
Hemodialysis duration, years3.52±2.063.37±2.520.321
Smoking, n (%)7 (20.0)8 (24.2)0.673
Drinking, n (%)6 (17.1)5 (15.2)0.824
TC (mg/dL)169.6±23.5161.9±25.40.531
HDL-C (mg/dL)54.8±16.451.6±13.30.314
LDL-C (mg/dL)94.5±22.189.5±22.60.273
TG (mg/dL)114.8±26.7110.2±23.90.164
CRP (μg/mL)5.8±3.66.1±3.40.198
Adiponectin (μg/mL)8.7±2.98.3±2.40.207
AST (IU/L)24.8±6.723.2±5.90.185
ALT (IU/L)18.9±4.319.4±5.50.298
Plasma creatinine (μM)354.6±48.7361.2±50.30.293
HbA1c (%)5.8±0.55.7±0.60.592
Lipid-lowering agents, cases (%)0.934
 Statin23 (65.7)22 (66.7)
 Fibrate3 (8.6)2 (6.1)
 Nicotinic acid and derivatives2 (5.7)1 (3.0)
 Anion exchange resin2 (5.7)3 (9.1)
 Others5 (14.3)6 (18.2)
Antiplatelet agents, cases (%)
 Cilostazol2 (5.7)2 (6.1)0.819
 Ticlopidine2 (5.7)2 (6.1)
 Dipyridamole3 (8.6)2 (6.1)
 Aspirin24 (68.6)25 (75.8)
 Sarpogrelate2 (5.7)1 (3.0)
 Clopidogrel2 (5.7)1 (3.0)
TVC, cases (%)7 (20.0)6 (18.2)0.849
AVF, cases (%)2 (5.7)3 (9.1)0.946
Anuric, cases (%)9 (25.7)11 (33.3)0.491
Albuminuria, cases (%)20 (57.1)18 (54.5)0.829
Serum protein (g/dL)6.6±1.26.4±1.00.269
Serum albumin(g/dL)2.9±0.62.8±0.70.351
TVC – tunneled central venous catheter; AVF – arteriovenous fistula. Chi-square was used for analyzing the statistical difference of count data and -student test was used for analyzing the statistical difference of measured data. The statistical difference was insignificant if P>0.05.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750