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13 July 2021: Clinical Research

Risk Factors for Fentanyl-Induced Cough Following General Anesthesia in Adults: A Retrospective Study from a Single Center in China

Xiao Zhao ABCDEF* , Hong Wang ABCDEF* , Hui-Juan Wang BCDEF , Yun Wang BCDEF , Yi-An Xing BCD , Shi-Tong Li ABC* , Lian-Hua Chen ABC*

DOI: 10.12659/MSM.930369

Med Sci Monit 2021; 27:e930369

Table 4 The risk factors for the incidence of vomiting by multivariate logistic regression analysis.

Variablesβ valueSDWald chi-squareOR (95% CI)P value
Gender0.5490.5301.0751.732 (0.613–4.891)0.300
Age (years)−0.0130.0160.6940.987 (0.956–1.018)0.405
Type of surgery0.0480.5300.0081.049 (0.371–2.962)0.928
Operative time (min)−0.0010.0060.0230.999 (0.988–1.011)0.879
BMI0.0020.0850.0011.002 (0.849–1.183)0.981
Intraoperative blood loss (ml)−0.0010.0020.3340.999 (0.996–1.002)0.563
Smoking status−0.1010.6940.0210.904 (0.232–3.521)0.884
Alcohol intake0.3500.8120.1861.419 (0.289–6.972)0.667
Pharyngitis0.2600.5190.2511.297 (0.469–3.585)0.617
History of gastroesophageal reflux0.6820.8710.6131.977 (0.359–10.901)0.434
Other digestive tract diseases−0.1141.1220.0100.892 (0.099–8.044)0.919
Hypertension−0.2280.7000.1060.796 (0.202–3.138)0.745
Diabetes mellitus−0.9231.0950.7100.397 (0.046–3.399)0.399
History of asthma−0.4381.0950.1600.645 (0.075–5.519)0.689
Psychiatric history−10.009194.3350.0030.000 (0.000–1.18E161)0.959
History of respiratory infection (within 2 months)−9.857181.4880.0030.000 (0.000–1.59E150)0.957
History of surgery0.2891.0960.0701.335 (0.156–11.436)0.792
Lidocaine (2%ml)−0.0680.1490.2100.934 (0.698–1.250)0.647
Palliative (Dexmedetomidinevs midazolam)−0.4880.5210.8760.614 (0.221–1.706)0.349
Sufentanil (ug).
 159.906222.4550.00220048.52 (0.000–4.53E193)0.965
 209.886222.4590.00219651.67 (0.000–4.47E193)0.965
Propofol (mg)0.0200.0230.7821.021 (0.975–1.068)0.377
Rocuronium bromide−0.0010.0600.0000.999 (0.888–1.125)0.990
Sufentanil0.0090.0370.0621.009 (0.939–1.084)0.803
BMI – body mass index; CI – confidence interval; OR – odds ratio; SD – standard deviation.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750