02 August 2021 : Meta-Analysis
Association Between TLR4 Gene Polymorphisms and Risk of Preeclampsia: Systematic Review and Meta-Analysis
Manni Sun1BE, Hui Jiang1BF, Tao Meng1AF, Peiyan Liu1BC, Haiying Chen1ACG*DOI: 10.12659/MSM.930438
Med Sci Monit 2021; 27:e930438
Table 1 Characteristics of the included studies.
| First Author | Published Year | Country | Race | Genotyping method | Cases/controls | Specimen | Source of cases | Source of controls | HWE (P) | NOS score |
|---|---|---|---|---|---|---|---|---|---|---|
| Vamvakopoulou | 2019 | Greece | Caucasian | Automated cycle sequencing | 84/94 | Blood | EOP | Heathy women | >0.05 | 7 |
| Mohammadpour-Gharehbagh | 2019 | Iran | Caucasian | PCR-RFLP | 111/115 | Placenta | PE | Healthy pregnancies | >0.05 | 7 |
| Franchim | 2011 | Brazil | Mixed | PCR-RFLP | 109/174 | Blood | PE | Healthy pregnancies | >0.05 | 8 |
| Xie | 2010 | Canada | Caucasian | RT-PCR | 94/76 | Blood | PE | Healthy pregnancies | >0.05 | 8 |
| Molvare | 2008 | Hungary | Caucasian | PCR-RFLP | 180/172 | Blood | PE | Healthy pregnancies | >0.05 | 8 |