12 April 2021 : Clinical Research
Epidemiological and Clinical Characteristics of 217 Cases of COVID-19 in Jiangsu Province, China
Jun Zhou1E, Bing Chen2C, Yali Wang1D, Feng Wu1AG*DOI: 10.12659/MSM.930853
Med Sci Monit 2021; 27:e930853
Table 1 Clinical characteristics and laboratory findings on admission to hospital between control group and COVID-19 group.
| Control group (n=66) | COVID-19 group (n=217) | F/χ2 | P | |
|---|---|---|---|---|
| Sex | ||||
| Female | 38 (57.6) | 120 (58.0) | 0.01 | 0.75 |
| Male | 28 (42.4) | 97 (42.0) | ||
| Age | 46 | 48 | 1.63 | 0.20 |
| Signs and symptoms | ||||
| Cough | 24/66 (36.4) | 136/217 (55.4) | 8.42 | 0.01 |
| Fever | 31/66 (47.0) | 155/217 (71.4) | 14.26 | 0.00 |
| Sore throat | 10/66 (15.2) | 34/217 (15.7) | 0.10 | 0.90 |
| Dyspnoea | 0/66 (0.0) | 15/217 (6.9) | 4.82 | 0.02 |
| Fatigue | 10/66 (15.2) | 45/217 (20.7) | 1.01 | 0.32 |
| Diarrhea | 5/66 (7.6) | 32/217 (12.3) | 1.17 | 0.28 |
| Vomiting | 3/66 (4.5) | 12/217 (5.5) | 0.09 | 0.75 |
| Headache | 5/66 (7.1) | 38/217 (17.5) | 0.83 | 0.36 |
| Other | 8/66 (12.1) | 38/217 (17.5) | 1.08 | 0.30 |
| Laboratory findings | ||||
| White cell count, ×10/L | 6.26±2.19 | 5.18±2.05 | 7.00 | 0.00 |
| Neutrophil, ×10/L | 3.76±1.73 | 3.26±1.93 | 1.55 | 0.21 |
| Lymphocyte, ×10/L | 2.00±1.07 | 1.42±0.68 | 18.77 | 0.00 |
| Hemoglobin (g/l) | 137.48±17.28 | 133.18±20.90 | 0.87 | 0.34 |
| Blood platelet, ×10/L | 225.24±76.56 | 196.62±69.52 | 0.06 | 0.81 |
| C-reactive protein (mg/l) | 11.64±4.48 | 44.33±9.40 | 3.54 | 0.03 |
| Procalcitonin (ng/ml) | 0.40±1.79 | 0.41±2.28 | 0.13 | 0.90 |
| ALT (u/l) | 34.23±44.15 | 30.00±23.73 | 0.78 | 0.43 |
| AST (u/l) | 29.60±27.75 | 27.37±15.64 | 0.56 | 0.58 |
| Total bilirubin (umol/l) | 11.97±6.09 | 15.39±28.44 | 0.67 | 0.51 |
| BUN (umol/l) | 4.46±3.83 | 4.51±4.57 | 0.10 | 0.92 |
| CRE (umol/l) | 4.46±3.84 | 4.39±4.16 | 1.90 | 0.06 |
| CK (u/l) | 98.08±144.33 | 101.00±315.86 | 0.06 | 0.96 |
| CK-MB (u/l) | 6.55±6.70 | 3.65±5.56 | 2.75 | 0.00 |
| CD3 T cell | 1352.71±542.93 | 1003.07±512.99 | 5.36 | 0.02 |
| CD4 T cell | 625.14±289.92 | 487.34±208.20 | 4.93 | 0.02 |
| CD8 T cell | 436.07±209.95 | 319.64±149.24 | 3.29 | 0.04 |
| CD4/CD8 | 1.66±0.72 | 1.84±0.86 | 0.05 | 0.82 |
| APTT (s) | 30.43±5.87 | 34.63±17.31 | 4.94 | 0.00 |
| PT (s) | 10.53±4.48 | 8.37±5.59 | 3.37 | 0.03 |
| Fig (g/l) | 3.15±1.39 | 3.51±1.15 | 1.21 | 0.23 |
| D-dimer (mg/l) | 0.22±0.24 | 1.35±2.21 | 5.60 | 0.00 |