12 April 2021: Clinical Research
Epidemiological and Clinical Characteristics of 217 Cases of COVID-19 in Jiangsu Province, China
Jun Zhou 1E , Bing Chen 2C , Yali Wang 1D , Feng Wu 1AG*DOI: 10.12659/MSM.930853
Med Sci Monit 2021; 27:e930853
Table 3 Clinical characteristics and laboratory findings on admission to hospital among the 3 groups.
| Mild (n=41) | Moderate (n=161) | Severe+critical (n=15) | F | P value | |
|---|---|---|---|---|---|
| Fever | 11/41 (26.8) | 101/161 (62.7) | 11/15 (73.3) | 18.97 | 0.00 |
| Cough | 4/41 (36.6) | 100/161 (62.1) | 10/15 (66.7) | 13.90 | 0.00 |
| Sore throat | 4/41 (9.8) | 15/161 (9.3) | 2/15 (13.3) | 0.25 | 0.88 |
| Dyspnoea | 0/41 (0.0) | 7/161 (4.3) | 11/15 (73.3) | 90.42 | 0.00 |
| Fatigue | 2/41 (4.9) | 37/161 (23.3) | 6/15 (40.0) | 10.15 | 0.01 |
| Diarrhea | 1/41 (2.4) | 20/161 (12.4) | 3/15 (20.0) | 4.62 | 0.09 |
| Vomiting | 1/41 (2.4) | 9/161 (5.6) | 2/15 (13.3) | 2.50 | 0.28 |
| Headache | 2/41 (4.9) | 7/161 (5.0) | 1/15 (6.7) | 0.08 | 0.96 |
| Other | 4/41 (9.8) | 9/161 (5.6) | 3/15 (20) | 4.59 | 0.10 |
| White cell count, (WBC, ×10/L) | 5.77±1.94 | 4.83±2.02 | 5.69±3.10 | 3.70 | 0.03 |
| Neutrophil, (×10/L) | 3.75±1.82 | 2.99±1.81 | 4.75±3.09 | 5.35 | 0.02 |
| Lymphocyte, (×10/L) | 1.48±0.54 | 1.37±0.63 | 0.64±0.23 | 7.27 | 0.00 |
| Hemoglobin (g/l) | 134.03±16.48 | 133.38±22.79 | 127.78±13.75 | 0.33 | 0.72 |
| Blood platelet, (×10/L) | 227.56±75.22 | 189.84±65.93 | 150.11±37.53 | 7.14 | 0.00 |
| C-reactive protein (CRP, mg/l) | 9.81±12.22 | 24.78±27.56 | 78.73±62.37 | 19.06 | 0.00 |
| Procalcitonin (PCT, ng/ml) | 0.04±0.06 | 0.33±1.96 | 2.15±5.76 | 2.69 | 0.07 |
| ALT (U/L) | 24.91±13.62 | 32.34±27.88 | 25.21±15.11 | 1.33 | 0.27 |
| AST (U/L) | 22.08±6.16 | 29.47±18.93 | 35.28±10.59 | 3.04 | 0.06 |
| Total bilirubin (umol/l) | 10.02±4.66 | 13.18±12.02 | 69.43±107.57 | 19.10 | 0.01 |
| BUN (umol/l) | 4.05±1.29 | 4.21±2.82 | 11.60±17.89 | 8.46 | 0.01 |
| CRE (umol/l) | 59.00±16.05 | 64.75±29.20 | 91.45±23.35 | 1.58 | 0.02 |
| CD3 T cell count(/ul) | 1355.33±871.15 | 884.8±346.96 | 567.25±226.22 | 3.80 | 0.03 |
| CD4 T cell count(/ul) | 555.67±147.23 | 561.88±205.60 | 276.25±94.44 | 3.82 | 0.03 |
| CD8 T cell count(/ul) | 192.50±83.24 | 359.22±210.34 | 192.50±83.24 | 3.51 | 0.04 |
| CD4/CD8 | 1.20±0.64 | 1.87±0.86 | 1.97±0.96 | 0.91 | 0.41 |
| APTT (s) | 31.53±7.74 | 32.96±6.37 | 40.48±14.86 | 7.30 | 0.00 |
| PT (s) | 4.33±5.21 | 8.96±5.46 | 9.19±5.77 | 11.71 | 0.00 |
| FIB (g/l) | 3.52±0.78 | 3.47±1.17 | 3.84±1.82 | 0.57 | 0.55 |
| D-dimer (mg/l) | 0.58±0.44 | 1.21±1.76 | 6.83±4.25 | 60.89 | 0.00 |
| Reference normal ranges: CD3+ T cell (1441±388/μl), CD4+ T cell (763±249/μl), CD8+ T cell (548±231/μl), CD4+/CD8+(1.6±0.8). | |||||