07 December 2021 : Animal Research
Tissue-Protective Effect of Erdosteine on Multiple-Organ Injuries Induced by Fine Particulate Matter
Lei Cao1ACDE, Fen Ping2AG*, Fengrui Zhang2BCF, Haixiang Gao3CDF, Ping Li2BCF, Xiaohui Ning2BCF, Guohuan Cui2DF, Zheng Ma4BC, Xin Jiang5CD, Suyan Li6CD, Shuzhi Han2ACDGDOI: 10.12659/MSM.930909
Med Sci Monit 2021; 27:e930909
Supplementary Table 1 Comparisons of cytokine level in rat serum of each group (n=10).
| Group | IL-6 (pg/ml) | IL-1β (pg/ml) | TNF-α (pg/ml) | 8-OHdG (ng/ml) | 4-HNE (ug/ml) | PCC (nmol/mg·prot) |
|---|---|---|---|---|---|---|
| Blank control group | 4.725±1.628 | 15.605±3.673 | 3.797±1.337 | 1.238±0.130 | 5.359±1.031 | 5.679±1.012 |
| Saline group | 4.980±1.690 | 16.282±3.291 | 2.774±0.923 | 1.190±0.127 | 5.767±1.180 | 5.990±1.402 |
| PM2.5 exposure group | 10.978±2.572 | 29.650±5.611 | 14.513±4.451 | 2.457±0.296 | 8.845±1.695 | 25.782±2.644 |
| Erdosteine intervention group | 7.562±1.989 | 24.133±4.911 | 6.619±1.491 | 1.669±0.236 | 7.416±1.650 | 16.137±2.43 |
| F | 21.053 | 22.574 | 45.758 | 18.277 | 13.420 | 231.090 |
| In the above table, equal letters indicate no statistical differences, >0.05; different letters indicate statistical differences, | ||||||