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19 August 2021: Lab/In Vitro Research

Hyperglycemia Promotes Liver Metastasis of Colorectal Cancer via Upregulation of Integrin αvβ6

Ben Wang 1ABEG , Shanjie Wang 2B , Wenke Wang 3BC , Enyu Liu 1BD , Sen Guo 1EF , Chuanzong Zhao 1CF , Jun Niu 1AD* , Zongli Zhang 1A*

DOI: 10.12659/MSM.930921

Med Sci Monit 2021; 27:e930921

Table 1 Comparison of clinicopathological parameters between non-DM group and DM group.

Clinical factorNo.Non-DMDMP***
No. of patients20314756
Differentiation* NS
Tumor invasion* NS
Lymph node status* NS
AJCC stage at diagnosis* NS
Lymphovascular invasion* 0.012
Liver metastasis** 0.025
* Clinicopathological diagnosis is determined according to TNM system confirmed by at least two pathologists;
** liver metastasis is diagnosed through imaging examination of CT or MR;
*** value was calculated by Chi-square test. NS – no significance.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750