Recent Advances in Maturation of Pluripotent Stem Cell-Derived Cardiomyocytes Promoted by Mechanical Stretch

Xingwang Gu; Fan Zhou; Junsheng Mu

doi:10.12659/MSM.931063

12 August 2021 : Review article

Recent Advances in Maturation of Pluripotent Stem Cell-Derived Cardiomyocytes Promoted by Mechanical Stretch

Xingwang Gu^1ABCF, Fan Zhou^2ABEF, Junsheng Mu^3ADFG*

DOI: 10.12659/MSM.931063

Med Sci Monit 2021; 27:e931063

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Background Parameters of Mechanical Stretch Effects of Mechanical Stretch on Maturation of PSC-CMs Signal Transduction Mechanisms Discussion and Summary References

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Table 1 Main differences between PSC-CMs and adult cardiomyocytes.

	PSC-CMs	Adult cardiomyocytes
Morphology
Sarcomere structure
Cardiac gene expression levels
Function
Electrophysiology
Calcium handling

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Recent Advances in Maturation of Pluripotent Stem Cell-Derived Cardiomyocytes Promoted by Mechanical Stretch

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