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10 September 2021: Clinical Research

Epidemiology and Mortality of Sepsis in Intensive Care Units in Prefecture-Level Cities in Sichuan, China: A Prospective Multicenter Study

Lianghai Cao 1ABE* , Min Xiao 2ABE* , Yong Wan 3AE* , Chaogui Zhang 1B , Xiaofeng Gao 4C , Xuemei Chen 5B , Xiangde Zheng 6B , Xianhua Xiao 7B , Mingquan Yang 8B , Yuanhua Zhang 9B

DOI: 10.12659/MSM.932227

Med Sci Monit 2021; 27:e932227

Table 4 Laboratory indices, severity scores, and hospitalization characteristics of sepsis patients during ICU admission.

All patients (n=294)Survival (n=125)Death (n=169)P
HGB minimum, g/L, median (Q1, Q3)86 (70–107)b 86 (73–106)87 (69–109)b0.875
PLT minimum, ×10/L, median (Q1, Q3)160 (91–245)b 164 (99–268)156 (84–228)b 0.101
PCT maximum, ng/ml, median (Q1, Q3)18.24 (4.69–58.11)d 20.89 (6.47–56.42)16.81 (3.98–60.00)d 0.381
ALB minimum, g/L, median (Q1, Q3)26.0 (23.0–29.3)c 26.8 (23.1–29.2)a 25.8 (22.9–29.4)b 0.748
PALB minimum, mg/L, median (Q1, Q3)49.4 (26.6–79.0)o 55.2 (31.7–88.2)k 45.8 (25.3–73.5)n 0.147
Blood total Ca minimum, mmol/L, median (Q1, Q3)1.84 (1.61–2.00)l 1.83 (1.67–1.97)g 1.85 (1.52–2.01)i 0.588
Blood P minimum, mmol/L, median (Q1, Q3)0.78 (0.54–1.08)m 0.69 (0.49–0.90)h 0.90 (0.58–1.36)j
LAC maximum, mmol/L, median (Q1, Q3)4.3 (2.6–7.5)c 3.3 (2.1–4.7)b 6.5 (3.2–10.1)a
PT maximum, s, median (Q1, Q3)17.6 (15.5–21.2)g 17.0 (14.7–19.7)f 18.0 (15.3–22.9)e 0.035
APTT maximum, s, median (Q1, Q3)47.5 (39.3–61.9)f 45.0 (38.8–54.4)c 48.9 (39.6–67.9)c 0.029
FIB minimum, g/L, median (Q1, Q3)3.22 (1.81–4.64)c 3.48 (2.15–4.77)a 3.17 (1.60–4.56)b 0.251
INR maximum, median (Q1, Q3)1.49 (1.25–1.81)d 1.44 (1.24–1.66)b 1.52 (1.27–1.94)b 0.063
APACHEII on day 1, median (Q1, Q3)26 (21–32)a 23 (17.5–26)29 (24–36)a
SOFA score on day 1, median (Q1, Q3)10 (7–12)a 8 (6–10)11 (8–14)a
Duration of ventilation, hours, median (Q1, Q3)48 (11–130)37 (0–116)55 (17–140)0.049
ICU stay, days, median (Q1, Q3)4 (2–8)5 (3–9)3 (1–7)
Hospital stay, days, median (Q1, Q3)8 (2–19)18 (11–26.5)3 (1–8)
IQR: P25-P75. ALB – albumin; APACHE II – Acute Physiology and Chronic Health Evaluation II; APTT – activated partial thrombin time; FIB – fibrinogen; HGB – hemoglobin; ICU – Intensive Care Unit; INR – International Standardized Ratio; LAC – lactic acid; PALB – prealbumin; PCT – procalcitonin; PLT – platelet; PT – prothrombin time; SOFA – Sequential Organ Failure Assessment. Number of Untested Cases:
a =1,
b =2,
c =3,
d =4,
e =5,
F =6,
g =11,
h =14,
i =19,
j =24,
k =26,
l =30,
m =38,
n =49,
o =75.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750