Development and Validation of a Prevalence Model for Latent Autoimmune Diabetes in Adults (LADA) Among Patients First Diagnosed with Type 2 Diabetes Mellitus (T2DM)

15 September 2021 : Clinical Research

Zhida Wang^1ABCDEF, Jie Zhang^2ABCDEF, Hui Xu^3CDEF, Liming Chen^1ADEFG*, Abigail Dove^4ADEF

DOI: 10.12659/MSM.932725

Med Sci Monit 2021; 27:e932725

Background Material and Methods Results Discussion Conclusions References

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Table 3 Single-variable logistic regression analysis in the model development group.

Clinical features	OR	95% CI		P value
Clinical features	OR	Lower limit	Upper limit	P value
Age				0.003
Ketosis				<0.001
Abdominal type obesity	0.527	0.240	1.157	0.110
History of tobacco smoking				0.009
HbA1c (%)				0.002
FPG				0.002
1hPG				0.001
2hPG				0.018
FINS	0.977	0.941	1.016	0.242
1hINS	0.992	0.980	1.004	0.185
2hINS	0.992	0.982	1.001	0.088
FCP	0.675	0.440	1.036	0.072
1hCP				0.011
2hCP				0.003
PG-AUC				<0.001
1hPG-AUC				<0.001
2hPG-AUC				0.002
INS-AUC	0.994	0.987	1.001	0.117
1hINS-AUC	0.986	0.967	1.006	0.167
2hINS-AUC	0.991	0.979	1.002	0.104
CP-AUC				0.004
1hCP-AUC				0.011
2hCP-AUC				0.003
HOMA2-β (%)				0.045
OR – odds ratio; CI – confidence interval.

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