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24 November 2021: Clinical Research

Discoidin Domain Receptor Tyrosine Kinase 1 (DDR1): A Novel Predictor for Recurrence of Hepatocellular Carcinoma After Curative Resection

Meng Xu CDEFG , Chenghao Cui AB*

DOI: 10.12659/MSM.933109

Med Sci Monit 2021; 27:e933109

Table 3 Univariate and multivariate Cox regression analysis of factors associated with recurrence.

VariablesUnivariate analysisMultivariate analysis
Age>50 vs ≤500.889 (0.551–1.434)0.629NANA
GenderMale vs Female1.076 (0.626–1.847)0.791NANA
AFP>400 ng/mL vs ≤400 ng/mL1.774 (1.100–2.862)1.568 (0.945–2.603)0.082
ALT>75 U/L vs ≤75 U/L0.969 (0.586–1.602)0.902NANA
Tumor size>5 cm vs ≤5 cm1.783 (1.092–2.912)1.375 (0.958–2.686)0.073
Tumor numberMultiple vs single3.426 (2.090–5.615)2.855 (1.686–4.836)
HbsAgPositive vs negative2.167 (0.989–4.747)0.053NANA
Liver cirrhosisYes vs no1.378 (0.669–2.681)0.361NANA
EncapsulationIncomplete vs complete1.115 (0.670–1.875)0.675NANA
Satellite lesionYes vs no0.601 (0.274–1.315)0.202NANA
Child-Pugh scoreB vs A1.505 (0.678–3.296)0.307NANA
Edmondson stageIII–IV vs I–II1.489 (0.920–2.408)0.105NANA
BCLC StageB-D vs 0-A1.230 (0.708–2.137)0.463NANA
DDR1 in serumHigh vs low1.902 (1.150–3.146)1.520 (1.078–2. 640)
DDR1 in tumorHigh vs low2.199 (1.275–3.790)1.811 (1.117–3.241)

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750