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31 January 2022: Meta-Analysis

Utility of Pretreatment Blood Platelet-To-Lymphocyte Ratio in Prediction of Clinical Outcomes and Chemosensitivity in Patients with Advanced Gastric Cancer: A Meta-Analysis

Xiulan Peng 1AE* , Wei Zeng 2BF* , Bing Tang 3CF* , Anbing He 1B , Min Zhang 1B , Renfeng Luo 4AB*

DOI: 10.12659/MSM.933449

Med Sci Monit 2022; 28:e933449

Table 1 Baseline characteristics of eligible studies for this meta-analysis.

AuthorYearCountrystudy designPeriodPatients nAge (y) median (range)Sex (M/F)
Aliustaoglu2010TurkeyRetrospective2004–200816860.1 (28–83)114/54
Lee2013KoreaRetrospective2007–201017455 (24–74)110/64
Wang2015ChinaRetrospective2010–201112068 (32–82)75/45
Aidemir2015TurkeyRetrospective2006–20135065 (40–82)30/20
Gong2017ChinaRetrospective2007–20159155 (26–70)69/22
Tang2018ChinaRetrospective2010–201610465 (31–78)74/30
Petrillo2019ItalyRetrospective2010–201715162 (26–85)97/54
Zhou2020ChinaRetrospective2010–201853755 (25–83)321/216
Ohe2020JapanRetrospective2005–20184165 (30–78)34/7
Wang2020ChinaRetrospective2010–201746660 (20–88)327/139
Zhai2021ChinaRetrospective2007–201430658 (28–85)245/61
Lee160NAChemotherapy14.9 (1–47.9)OS, PFS7
Gong161ROC curveMixed22 (8–67)OS8
Tang130.7ROC curveMixedNAOS7
Petrillo157MedianChemotherapy29 (20.4–37.5)OS8
Wang210.6ROC curveChemotherapyNAOS7
Zhou284ROC curveChemotherapyNAOS, PFS8
Zhao143.39ROC curvechemotherapy11.6OS8
Ohe180ROC curvechemotherapyNAOS7
Toyokawa172ROC curveMixed80 (69–124)OS9
Huang107.7X-tileMixed28.01 (1–99)OS8
Wang174.79MedianChemotherapyNAOS, PFS8
Gu154ROC curveMixed50 (4–83)DFS7
Zhai128ROC curveMixed11OS9
NA – not available; OS – overall survival; DFS – disease-free survival; NOS – Newcastle-Ottawa scale; ROC – receiver operating characteristics curve; PLR – platelet-to-lymphocyte ratio.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750