Epidemiology of Birth Defects in Eastern China and the Associated Risk Factors

17 January 2022 : Clinical Research

Qiao-Qiao Wang^1BEG*, Cha-Ying He^2AC, Jin Mei^3ADF, Yi-Lin Xu^4BC

DOI: 10.12659/MSM.933782

Med Sci Monit 2022; 28:e933782

Background Material and Methods Results Discussion Conclusions References

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Table 6 Logistic regression analysis of Down syndrome.

Factors	B	SE	Wald	P	Exp (B)
Family income (vs <1000)			37.054	<0.0001
1000–2000	−0.382	0.78	0.24	0.624	0.682
2000–4000	−0.681	0.77	0.782	0.376	0.506
4000–8000	−0.429	0.768	0.312	0.576	0.651
>8000	−0.953	0.765	1.551	0.213	0.385
Gravidity (vs 1)			7.215	0.027
2	−0.092	0.084	1.21	0.271	0.912
≥3	−0.262	0.097	7.205	0.007	0.77
Parity (vs 0)			33.372	<0.0001
1	0.454	0.098	21.598	<0.0001	1.575
≥2	0.739	0.132	31.412	<0.0001	2.093
Education level (vs illiteracy)			64.599	<0.0001
Elementary school	−0.244	0.490	0.249	0.618	0.783
Junior middle school	0.057	0.459	0.016	0.901	1.059
Senior middle school	0.724	0.459	2.486	0.115	2.062
College degree and above	0.802	0.457	3.075	0.079	2.23
Contraceptives (Yes or No)	0.232	0.109	4.54	0.033	1.262
Constant	−0.971	0.804	1.457	0.227	0.379

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