27 February 2022 : Clinical Research
Serum Uric Acid Levels in Relation to Atrial Fibrillation: A Case-Control Study
Xia Zhong1ABCDEF*, Huachen Jiao2ABCFG, Dongsheng Zhao1BD, Jing Teng1CFDOI: 10.12659/MSM.934007
Med Sci Monit 2022; 28:e934007
Table 2 Association between serum uric acid levels and atrial fibrillation.
| Total | Male | Female | ||||
|---|---|---|---|---|---|---|
| OR 95% CI | P value | OR 95% CI | P value | OR 95% CI | P value | |
| Model1 | 1.002 (1.000–1.003) | 0.006 | 1.000 (0.999–1.002) | 0.783 | 1.005 (1.003–1.007) | <0.001 |
| Model2 | 1.002 (1.000–1.004) | 0.004 | 1.001 (0.999–1.004) | 0.402 | 1.004 (1.001–1.007) | 0.008 |
| Model3 | 1.003 (1.002–1.005) | 0.001 | 1.002 (1.000–1.005) | 0.043 | 1.006 (1.003–1.009) | <0.001 |
| Model4 | 1.004 (1.002–1.006) | 0.014 | 1.003 (1.001–1.007) | 0.054 | 1.005 (1.002–1.009) | 0.005 |
| Model 1: Crude, no adjustment. Model 2: Adjusted for sex, hypertension, diabetes, CHD, β-blockers, CCBs, ACEI/ARB, and statins. Model 3: Adjusted for SCr, AST, ALT/AST, ALB, APOA1, APOB, A/G, and PAB. Model 4: Adjusted for all these factors. AF – atrial fibrillation; CHD – coronary heart disease; SCr – serum creatinine; FBG – fasting blood glucose; AST – aspartate aminotransferase; AST/ALT – aspartate aminotransferase/alanine aminotransferase; APOA1 – serum apolipoprotein A1; APOB – serum apolipoprotein B; ALB – albumin; A/G – albumin/globulin; PAB – prealbumin; CCBs – calcium channel blockers; ACEI/ARB – angiotensin-converting enzyme inhibitor/angiotensin receptor blocker. | ||||||