08 March 2022>: Review Articles
Adie’s Pupil: A Diagnostic Challenge for the Physician
Sui-yi Xu EG* , Mao-mei Song BC* , Ling Li DF* , Chang-xin Li A*DOI: 10.12659/MSM.934657
Med Sci Monit 2022; 28:e934657
Table 1 Literature review of Adie’s pupil cases from 2010 to 2020.
Literature review | Sex/age | Clinical manifestations | Unilateral/bilateral | Response to dilute pilocarpine | Accompanied disease | Treatment |
---|---|---|---|---|---|---|
Takata []7 | Male/30 | Blurred vision | Left | Left pupil constriction (0.125%) | Neurosyphilis | Penicillin G |
Camoriano []8 | Male/39 | Blurred vision | Right | Right pupil constriction (0.125%) | Neurosyphilis | Penicillin G |
Jivraj []9 | Female/38 | Blurred vision | Bilateral | Bilateral pupil constriction (0.1%) | Neurosyphilis | Penicillin G |
Rissardo []10 | Male/23 | Blurred vision | Left | NA | Neurosyphilis | Penicillin G |
Gu []11 | Male/41 | Blurred vision | Left | Left pupil constriction (0.5%) | Neurosyphilis | Ceftriaxone |
Pecero-Hormigo []12 | Male/33 | Blurred vision | Right | NA | Neurosyphilis | Penicillin G |
Reyes []13 | Male/30 | No | Bilateral | Bilateral pupil constriction (0.125%) | Neurosyphilis AIDS | Penicillin G |
Cerny []14 | Female/38 | Blurred vision, pain behind the eyeball, photophobia | Bilateral | Bilateral pupil constriction (0.1%) | AIDS | Tenofovir |
Ortiz-Seller []15 | Female/51 | Blurred vision, pain behind the eyeball | Bilateral | Bilateral pupil constriction (0.1%) | COVID-19 | Oral prednisone |
Ordás []16 | Male/62 | Blurred vision, diplopia | Left | Left pupil constriction (0.125%) | COVID-19 | Oral prednisone |
Karadžić []17 | Female/59 | Blurred vision | Left | Left pupil constriction (0.125%) | Viral hepatitis | NA |
Karadžić []17 | Female/55 | No | Left | Left pupil constriction (0.125%) | Viral hepatitis | NA |
Lana-Peixoto []18 | Female/33 | No | Left | Left pupil constriction (0.1%) | Leprosy | NA |
Lana-Peixoto []18 | Female/42 | No | Bilateral | Bilateral pupil constriction (0.1%) | Leprosy | Steroid, anti-leprosy drugs |
Bhagwan []19 | Female/35 | Blurred vision, redness of both eyes | Bilateral | Bilateral pupil constriction (0.1%) | Sjogren syndrome | NA |
Bhagwan []19 | Female/45 | Blurred vision | Bilateral | Bilateral pupil constriction (0.1%) | Sjogren syndrome | IVIg |
Miranda []20 | Female/51 | No | Right | Right pupil constriction (0.125%) | Sjogren syndrome | NA |
Robles-Cedeño []21 | Female/23 | Blurred vision, diplopia, photophobia | Bilateral | Bilateral pupil constriction (0.125%) | VKH syndrome | Steroid |
Narang []22 | Male/28 | Blurred vision | Bilateral | Bilateral pupil constriction (0.16%) | VKH syndrome | IVMP |
Garza []23 | Female/37 | Blurred vision, redness of both eyes | Bilateral | Bilateral pupil constriction (0.16%) | VKH syndrome | Prednisolone, tropicamide-phenylephrine, betamethasone |
Sevketoglu []24 | Male/5 | No | Left | Left pupil constriction (0.125%) | GBS | Plasmapheresis, IVIg |
Escorcio-Bezerra []25 | Female/23 | Blurred vision, diplopia | Bilateral | Bilateral pupil constriction (0.125%) | CIDP | Plasmapheresis, corticoids |
Matalia []26 | Female/16 | Blurred vision | Right | Right pupil constriction (0.125%) | Takayasu arteritis | NA |
Kaymakamzade []27 | Male/17 | Diplopia | NA | NA | MFS | IVIg |
Kaymakamzade []27 | Male/66 | Diplopia | Bilateral | Bilateral pupil constriction (0.125%) | MFS | IVIg |
Morimoto []28 | Female/42 | Photophobia | Left | Left pupil constriction (0.125%) | AAG | IVIg, IVMP |
Peyman []29 | Female/45 | Blurred vision photophobia | Left | Left pupil constriction (0.1%) | Breast cancer | NA |
Srinivasan []30 | Male/7 | No | Bilateral | Bilateral pupil constriction (0.125%) | Hodgkin lymphoma | Chemotherapy |
Horta []31 | Male/48 | No | Left | NA | Hodgkin lymphoma | Chemotherapy |
Zhang []32 | Female/50 | No | Right | Right pupil constriction (0.0625%) | Mediastinal small cell carcinoma | Chemotherapy |
Yamane []33 | Female/50 | Blurred vision | Left | Left pupil constriction (0.125%) | Adenoid cystic carcinoma | NA |
Han []34 | Female/36 | Blurred vision | Bilateral | Bilateral pupil constriction (0.125%) | Dorsal midbrain syndrome | Surgery |
Kim []35 | Female/2 | No | Left | Left pupil constriction (0.1%) | Inferior oblique myectomy | NA |
Babiano []36 | Male/NA | No | Right | Right pupil constriction (0.125%) | Traumatic brain injury | NA |
Tafakhori []37 | Female/27 | Blurred vision | Left | Left pupil constriction (0.125%) | Migraine | Pilocarpine(0.125%) |
Garrick []38 | Female/22 | No | NA | Pupil constriction | Dysautonomia | IVIg |
Colak []39 | Female/31 | Blurred vision | Left | Left pupil constriction (0.5%) | No | NA |
Batawi []40 | Male/40 | Blurred vision, photophobia | Right | Right pupil constriction (0.1%) | No | Pilocarpine (1%) |
Durán-Ferreras []41 | Female/16 | Blurred vision | Right | Right pupil constriction (0.125%) | No | NA |
Rivero Rodríguez []42 | Female/21 | Blurred vision, photophobia | Left | Left pupil constriction (0.125%) | No | NA |
NA – not available; AAG – autoimmune autonomic ganglionopathy; AIDS – acquired immunodeficiency syndrome; CIDP – chronic inflammatory demyelinating polyneuropathy; COVID-19 – coronavirus disease 2019; GBS – Guillain-Barre syndrome; IVIg – intravenous immunoglobulin; IVMP – intravenous methylprednisolone; MFS – Miller Fisher syndrome; VKH syndrome – Vogt-Koyanagi-Harada syndrome. |