Retrospective Study of 1255 Non-Anticoagulated Patients with Nonvalvular Atrial Fibrillation to Determine the Risk of Ischemic Stroke Associated with Left Atrial Spontaneous Echo Contrast on Transesophageal Echocardiography

11 December 2021 : Clinical Research

Kesen Liu^1ABCDEF, Yukun Li^1B, Kui Wu^1B, Junlei Li^1C, Yong Zhu^1CD, Fei Guo^1CD, Rong Bai^1AEF, Jianzeng Dong^1ADEFG*

DOI: 10.12659/MSM.934795

Med Sci Monit 2021; 27:e934795

Background Material and Methods Results Discussion Conclusions References

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Table 2 Predictors of left atrial spontaneous echo contrast on univariate logistic analysis.

Variables	OR	95% CI	P value
Age	1.025	1.007–1.044	0.008
Congestive heart failure	9.354	5.926–14.763	<0.001
Previous stroke/TIA	3.123	1.813–5.377	<0.001
Hypertension	1.277	0.893–1.825	0.18
Diabetes mellitus	1.182	0.755–1.851	0.464
Non-paroxysmal AF	17.094	10.244–28.523	<0.001
Vascular disease	2.139	0.914–5.008	0.08
CHA2DS2-VASc score	1.305	1.152–1.479	<0.001
Left atrial diameter	1.253	1.199–1.310	<0.001
Left atrial enlargement	7.784	5.176–11.706	<0.001
LVEF	0.914	0.891–0.938	<0.001
LVEF<50	7.461	4.072–13.671	<0.001
CRP	1.071	1.033–1.111	<0.001
Uric acid	1.004	1.002–1.006	<0.001
Homocysteine	1.023	1.003–1.044	0.026
eGFR	0.984	0.973–0.994	0.002
LASEC – left atrial spontaneous echo contrast; OR – odds ratio; CI – confidence interval; TIA – transient ischemic attack; AF – atrial fibrillation; LVEF – left ventricular ejection fraction; CRP – C-reactive protein; eGFR – estimated glomerular filtration rate.

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