Retrospective Study of 1255 Non-Anticoagulated Patients with Nonvalvular Atrial Fibrillation to Determine the Risk of Ischemic Stroke Associated with Left Atrial Spontaneous Echo Contrast on Transesophageal Echocardiography

11 December 2021: Clinical Research

Kesen Liu ^ABCDEF , Yukun Li ^B , Kui Wu ^B , Junlei Li ^C , Yong Zhu ^CD , Fei Guo ^CD , Rong Bai ^AEF , Jianzeng Dong ^ADEFG*

DOI: 10.12659/MSM.934795

Med Sci Monit 2021; 27:e934795

Table 2 Predictors of left atrial spontaneous echo contrast on univariate logistic analysis.

Variables	OR	95% CI	P value
Age	1.025	1.007–1.044	0.008
Congestive heart failure	9.354	5.926–14.763
Previous stroke/TIA	3.123	1.813–5.377
Hypertension	1.277	0.893–1.825	0.18
Diabetes mellitus	1.182	0.755–1.851	0.464
Non-paroxysmal AF	17.094	10.244–28.523
Vascular disease	2.139	0.914–5.008	0.08
CHA2DS2-VASc score	1.305	1.152–1.479
Left atrial diameter	1.253	1.199–1.310
Left atrial enlargement	7.784	5.176–11.706
LVEF	0.914	0.891–0.938
LVEF	7.461	4.072–13.671
CRP	1.071	1.033–1.111
Uric acid	1.004	1.002–1.006
Homocysteine	1.023	1.003–1.044	0.026
eGFR	0.984	0.973–0.994	0.002
LASEC – left atrial spontaneous echo contrast; OR – odds ratio; CI – confidence interval; TIA – transient ischemic attack; AF – atrial fibrillation; LVEF – left ventricular ejection fraction; CRP – C-reactive protein; eGFR – estimated glomerular filtration rate.