Retrospective Study of 1255 Non-Anticoagulated Patients with Nonvalvular Atrial Fibrillation to Determine the Risk of Ischemic Stroke Associated with Left Atrial Spontaneous Echo Contrast on Transesophageal Echocardiography

11 December 2021 : Clinical Research

Kesen Liu^1ABCDEF, Yukun Li^1B, Kui Wu^1B, Junlei Li^1C, Yong Zhu^1CD, Fei Guo^1CD, Rong Bai^1AEF, Jianzeng Dong^1ADEFG*

DOI: 10.12659/MSM.934795

Med Sci Monit 2021; 27:e934795

Background Material and Methods Results Discussion Conclusions References

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Table 3 Independent predictors of left atrial spontaneous echo contrast on multivariate logistic analysis.

Variables	OR	95% CI	P value
Age	1.042	1.013–1.071	0.004
Non-paroxysmal AF	10.010	5.768–17.370	<0.001
Previous stroke/TIA	2.405	1.242–4.661	0.009
Congestive heart failure	6.100	2.929–12.704	<0.001
Left atrial enlargement	3.369	2.111–5.377	<0.001
LVEF <50	1.873	0.728–4.816	0.193
CRP	1.040	0.994–1.089	0.86
Uric acid	1.001	0.999–1.004	0.253
eGFR	1.003	0.988–1.018	0.711
Homocysteine	1.003	0.974–1.033	0.847
LASEC – left atrial spontaneous echo contrast; OR – odds ratio; CI – confidence interval; AF – atrial fibrillation; TIA – transient ischemic attack; LVEF – left ventricular ejection fraction; CRP – C-reactive protein; eGFR – estimated glomerular filtration rate.

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