16 April 2022: Database Analysis
Identification of Novel Genes and Associated Drugs in Cervical Cancer by Bioinformatics Methods
Dan Wang 1CDE , Yanling Liu 2F , Shuyu Cheng 1D , Guoyan Liu 123AG*DOI: 10.12659/MSM.934799
Med Sci Monit 2022; 28:e934799
Table 1 All 78 commonly differentially expressed genes (DEGs) were detected from four profile datasets, including 51 up-regulated genes and 27 down-regulated genes in the cervical cancer compared to normal cervical tissues.
| DEGs | Gene name |
|---|---|
| Upregulated | TPX2, KNTC1, FOXM1, CDK1, RYR1, AURKA, KIF14, C1orf112, SPP1, ENO2, MCM10, TYMS, MCM5, MELK, ZWINT, PLOD2, STAT1, MMP12, ECT2, KIF23, MCM7, PRC1, CEP55, MOCOS, MCM4, DLGAP5, RAD51AP1, NEK2, GINS2, CDC25A, NUP62CL, DSG2, CXCL8, CENPN, CDC20, PLK4, RFC4, ISG15, ASPM, ATAD2, TOP2A, FANCI, SYCP2, MCM6, KIF20A, AIM2, CDKN2A, LHX2, NCAPG, CENPF, NUSAP1 |
| Downregulated | BBOX1, ZSCAN18, UPK1A, ENDOU, MAL, KLF4, ABCA8, EDN3, SPON1, TGM3, HPGD, CWH43, IGFBP5, KRT2, ALOX12, CYP2C18, CRNN, PEG3, SOSTDC1, PPP1R3C, SLURP1, ZNF91, AR, IVL, CFD, HOPX |