12 July 2022>: Database Analysis
LINC00963 May Be Associated with a Poor Prognosis in Patients with Cervical Cancer
Aimin Chang ACDEFG* , Ying Shi BCDE , Ping Wang BCD , Jingjing Ren BCFDOI: 10.12659/MSM.935070
Med Sci Monit 2022; 28:e935070
Table 1 Characteristics of patients with cervical and endocervical cancers in The Cancer Genome Atlas.
Characters | level | Low expression of LINC00963 | High expression of LINC00963 | p |
---|---|---|---|---|
n | 152 | 152 | ||
T stage (%) | T1 | 62 (53.0%) | 78 (62.9%) | 0.141 |
T2 | 36 (30.8%) | 35 (28.2%) | ||
T3 | 11 (9.4%) | 9 (7.3%) | ||
T4 | 8 (6.8%) | 2 (1.6%) | ||
N stage (%) | N0 | 72 (78.3%) | 61 (60.4%) | 0.012 |
N1 | 20 (21.7%) | 40 (39.6%) | ||
M stage (%) | M0 | 60 (89.6%) | 56 (94.9%) | 0.334 |
M1 | 7 (10.4%) | 3 (5.1%) | ||
Clinical stage (%) | Stage I | 74 (50.3%) | 88 (58.7%) | 0.401 |
Stage II | 35 (23.8%) | 34 (22.7%) | ||
Stage III | 25 (17.0%) | 20 (13.3%) | ||
Stage IV | 13 (8.8%) | 8 (5.3%) | ||
Radiation therapy (%) | No | 61 (40.1%) | 61 (40.1%) | 1 |
Yes | 91 (59.9%) | 91 (59.9%) | ||
Primary therapy outcome (%) | CR | 80 (77.7%) | 101 (88.6%) | 0.140 |
PD | 15 (14.6%) | 7 (6.1%) | ||
PR | 5 (4.9%) | 3 (2.6%) | ||
SD | 3 (2.9%) | 3 (2.6%) | ||
Histological type (%) | Adenosquamous | 9 (5.9%) | 43 (28.3%) | |
Squamous cell carcinoma | 143 (94.1%) | 109 (71.7%) | ||
Histologic grade (%) | G1 | 5 (3.7%) | 13 (9.4%) | 0.147 |
G2 | 71 (53.0%) | 64 (46.4%) | ||
G3 | 58 (43.3%) | 60 (43.5%) | ||
G4 | 0 (0.0%) | 1 (0.7%) | ||
Menopause status (%) | Peri | 12 (11.0%) | 13 (10.7%) | 0.921 |
Post | 40 (36.7%) | 42 (34.4%) | ||
Pre | 57 (52.3%) | 67 (54.9%) | ||
Birth control pill history (%) | No | 43 (58.9%) | 46 (54.8%) | 0.718 |
Yes | 30 (41.1%) | 38 (45.2%) | ||
Keratinizing squamous cell carcinoma present (%) | No | 64 (42.1%) | 55 (36.2%) | 0.347 |
PIK3CA status (%) | Mut | 38 (26.2%) | 44 (31.2%) | 0.422 |
WT | 107 (73.8%) | 97 (68.8%) | ||
Age (median [IQR]) | 47.00 [40.00,60.00] | 45.00 [36.75,55.00] | 0.168 | |
Height (median [IQR]) | 161.00 [156.25,165.00] | 160.00 [157.00,165.00] | 0.617 | |
Weight (median [IQR]) | 68.00 [57.00,81.25] | 72.00 [60.50,84.00] | 0.075 |