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12 July 2022: Database Analysis

LINC00963 May Be Associated with a Poor Prognosis in Patients with Cervical Cancer

Aimin Chang ACDEFG* , Ying Shi BCDE , Ping Wang BCD , Jingjing Ren BCF

DOI: 10.12659/MSM.935070

Med Sci Monit 2022; 28:e935070

Table 1 Characteristics of patients with cervical and endocervical cancers in The Cancer Genome Atlas.

CharacterslevelLow expression of LINC00963High expression of LINC00963p
n152152
T stage (%)T162 (53.0%)78 (62.9%)0.141
T236 (30.8%)35 (28.2%)
T311 (9.4%)9 (7.3%)
T48 (6.8%)2 (1.6%)
N stage (%)N072 (78.3%)61 (60.4%)0.012
N120 (21.7%)40 (39.6%)
M stage (%)M060 (89.6%)56 (94.9%)0.334
M17 (10.4%)3 (5.1%)
Clinical stage (%)Stage I74 (50.3%)88 (58.7%)0.401
Stage II35 (23.8%)34 (22.7%)
Stage III25 (17.0%)20 (13.3%)
Stage IV13 (8.8%)8 (5.3%)
Radiation therapy (%)No61 (40.1%)61 (40.1%)1
Yes91 (59.9%)91 (59.9%)
Primary therapy outcome (%)CR80 (77.7%)101 (88.6%)0.140
PD15 (14.6%)7 (6.1%)
PR5 (4.9%)3 (2.6%)
SD3 (2.9%)3 (2.6%)
Histological type (%)Adenosquamous9 (5.9%)43 (28.3%)
Squamous cell carcinoma143 (94.1%)109 (71.7%)
Histologic grade (%)G15 (3.7%)13 (9.4%)0.147
G271 (53.0%)64 (46.4%)
G358 (43.3%)60 (43.5%)
G40 (0.0%)1 (0.7%)
Menopause status (%)Peri12 (11.0%)13 (10.7%)0.921
Post40 (36.7%)42 (34.4%)
Pre57 (52.3%)67 (54.9%)
Birth control pill history (%)No43 (58.9%)46 (54.8%)0.718
Yes30 (41.1%)38 (45.2%)
Keratinizing squamous cell carcinoma present (%)No64 (42.1%)55 (36.2%)0.347
PIK3CA status (%)Mut38 (26.2%)44 (31.2%)0.422
WT107 (73.8%)97 (68.8%)
Age (median [IQR])47.00 [40.00,60.00]45.00 [36.75,55.00]0.168
Height (median [IQR])161.00 [156.25,165.00]160.00 [157.00,165.00]0.617
Weight (median [IQR])68.00 [57.00,81.25]72.00 [60.50,84.00]0.075

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750