22 January 2022 : Clinical Research
A Questionnaire-Based Study to Obtain a Consensus from 5 Polish Burns Centers on Eschar Removal by Bromelain-Based Enzymatic Debridement (Nexobrid®) in Burns Following the 2020 Updated European Consensus Guidelines
Tomasz Korzeniowski12ABCDEFG*, Jerzy Strużyna13ACDEFG, Anna M. Chrapusta4ABCDE, Andrzej Krajewski5ABDE, Marek Kucharzewski6ABDEF, Krzysztof Piorun
5ABCE, Jakub Nowakowski7BCDF, Agnieszka Surowiecka1ACDE, Magdalena Kozicka12ABDF, Kamil Torres12BDEG
DOI: 10.12659/MSM.935632
Med Sci Monit 2022; 28:e935632
Table 1 Consensus statements and agreement on indications and usage of enzymatic debridement.
| No | Statement | Agreement | Likert scale | Consensus |
|---|---|---|---|---|
| 1 | Enzymatic debridement is one of the early eschar removal methods for burns | 100% | 5/5 strongly agree | Yes |
| 2 | Nexobrid-based enzymatic debridement is a safe tool as long as is it used by an experienced burn team | 100% | 4/5 strongly agree1/5 agree | Yes |
| 3 | Enzymatic debridement is not recommended for use in chemical or electrical burns | 100% | 3/5 strongly agree1/5 agree1/5 somewhat agree | Yes |
| 4 | Enzymatic debridement is particularly beneficial in treating burns of the upper limbs, including the arms, as well as the face and the groin | 100% | 4/5 strongly agree1/5 agree | Yes |
| 5 | Enzymatic debridement can be used in extensive burns but needs to be restricted to 15% of the body surface area per session | 100% | 4/5 strongly agree1/5 agree | Yes |
| 6 | Given the selective nature of enzymatic debridement, it is recommended for use particularly in treatment of mixed deep dermal and full-thickness burns | 100% | 5/5 strongly agree | Yes |
| 7 | Using enzymatic debridement as a means of early removal of eschar in circumferential burns allows avoidance of surgical escharotomy | 100% | 4/5 strongly agree1/5 agree | Yes |
| 8 | Enzymatic debridement can be particularly useful in cases of limited access to hospital resources, such as in mass disasters | 80% | 4/5 strongly agree1/5 disagree | No |