21 February 2022 : Clinical Research
Effect of Shengbai Decoction on Chemotherapy-Induced Myelosuppression and Survival of Gastric Cancer Patients After Radical Resection: A Retrospective Study
Linhua Yao1ABCEF, Wenming Feng2ABEF, Yulong Tao2ABCEF, Chengwu Tang2ABCDEF*DOI: 10.12659/MSM.935936
Med Sci Monit 2022; 28:e935936
Table 3 Treatment-related adverse events.
| Adverse event | Control group (n=58) | SD group (n=57) | P value | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Grade | Grade | ||||||||
| 1 | 2 | 3 | 4 | 1 | 2 | 3 | 4 | ||
| Neutropenia | 20 | 32 | 4 | 2 | 30 | 24 | 2 | 1 | 0.0430 |
| Thrombocytopenia | 23 | 24 | 2 | 0 | 22 | 16 | 1 | 0 | 0.0323 |
| Anemia | 21 | 25 | 3 | 2 | 26 | 16 | 2 | 1 | 0.0416 |
| Nausea/vomiting | 24 | 25 | 3 | 0 | 22 | 26 | 2 | 0 | 0.9129 |
| Diarrhea | 7 | 8 | 0 | 0 | 6 | 5 | 0 | 0 | 0.3785 |
| Elevated creatinine level | 5 | 2 | 0 | 0 | 4 | 3 | 0 | 0 | 0.9450 |
| Elevated ALT/AST level | 3 | 3 | 0 | 0 | 3 | 2 | 0 | 0 | 0.7630 |
| Elevated total serum bilirubin level | 2 | 2 | 0 | 0 | 3 | 2 | 0 | 0 | 0.7185 |
| Stomatitis | 7 | 4 | 1 | 0 | 6 | 5 | 1 | 0 | 0.9277 |
| Hand-foot syndrome | 21 | 3 | 2 | – | 19 | 2 | 2 | – | 0.6165 |
| Paresthesia | 20 | 9 | 0 | 0 | 17 | 8 | 0 | 0 | 0.5435 |
| ALT – alanine aminotransferase; AST – aspartate aminotransferase. | |||||||||