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08 June 2022: Clinical Research

Association Between Variants of the Mannose-Binding Lectin 2 Gene and Susceptibility to Sepsis in the Hainan Island

Shaowen Cheng 123ABCDEFG* , Junyu Zhu 4ABCDE* , Xini Liu 5CDEF* , Jian Yang 12AEF , Yudie Wang 6BCD , Wei Zhang 6BCD , Zhihua Hu 7AEF* , Jiemiao Ouyang 8ADF* , Huaping Liang 4AEFG*

DOI: 10.12659/MSM.936134

Med Sci Monit 2022; 28:e936134

Table 2 The rs1800450 genotype distributions of Hardy-Weinberg equilibrium in total (n/%).

SNPsNGGGAAAχ2P
rs1800450581441 (75.9)127 (21.9)13 (2.2)1.1280.288
Only the mutation site of rs1800450 G/A was found in the three site mutations of MBL2 gene polymorphisms (rs1800450, rs180045, and rs50307371). The rs1800450 genotype distributions were consistent with the Hardy-Weinberg equilibrium (χ=1.128, P=0.288; Table 2).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750