08 June 2022>: Clinical Research
Association Between Variants of the Mannose-Binding Lectin 2 Gene and Susceptibility to Sepsis in the Hainan Island
Shaowen Cheng 123ABCDEFG* , Junyu Zhu 4ABCDE* , Xini Liu 5CDEF* , Jian Yang 12AEF , Yudie Wang 6BCD , Wei Zhang 6BCD , Zhihua Hu 7AEF* , Jiemiao Ouyang 8ADF* , Huaping Liang 4AEFG*DOI: 10.12659/MSM.936134
Med Sci Monit 2022; 28:e936134
Table 2 The rs1800450 genotype distributions of Hardy-Weinberg equilibrium in total (n/%).
SNPs | N | GG | GA | AA | χ2 | P |
---|---|---|---|---|---|---|
rs1800450 | 581 | 441 (75.9) | 127 (21.9) | 13 (2.2) | 1.128 | 0.288 |
Only the mutation site of rs1800450 G/A was found in the three site mutations of MBL2 gene polymorphisms (rs1800450, rs180045, and rs50307371). The rs1800450 genotype distributions were consistent with the Hardy-Weinberg equilibrium (χ=1.128, P=0.288; Table 2). |