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14 May 2022: Clinical Research

Case-Control Study to Investigate the Association Between Serum Apolipoprotein B/A1 Ratio and Atrial Fibrillation by Sex in 920 Patients from China

Xia Zhong 1ACE , Huachen Jiao 2DFG* , Dongsheng Zhao 1BC , Jing Teng 1AF , Mengqi Yang 1BE

DOI: 10.12659/MSM.936425

Med Sci Monit 2022; 28:e936425

Table 1 Clinical characteristics.

VariableAF group (n=920)Control group (n=920)P value
Age, years68.62±10.3668.08±11.460.289
Male, n (%)460 (50.00)457 (49.67)0.889
Hypertension, n (%)618 (67.17)308 (33.48)*
CHD, n (%)812 (88.26)227 (24.67)*
Diabetes, n (%)274 (29.787)153 (16.63)*
 APOA1, g/L1.13±0.261.22±0.25*
 APOB, g/L0.79±0.380.99±0.24*
APOB/APOA1 ratio0.71±0.410.84±0.25*
Lp (a), mg/L23.67±27.0822.54±24.490.348
TC, mmol/L4.19±1.095.03±1.10*
TG, mmol/L1.24±0.881.38±1.25*
LDL-C, mmol/L1.08±0.301.20±0.31*
HDL-C, mmol/L2.50±0.892.97±0.86*
AST, U/L25.42±46.3120.81±10.93*
ALT, U/L22.38±27.7420.40±13.860.053
ALB, g/L38.02±4.6440.10±4.13*
PAB, g/L19.55±5.9222.29±5.50*
SUA, mg/dL5.89±1.765.12±1.37*
SCr, μmoI/L78.55±52.1365.04±27.00*
Statins, n (%)605 (65.76)211 (22.93)*
CCBs, n (%)331 (35.98)161 (17.50)*
β-blockers, n (%)721 (78.37)153 (16.63)*
ACEI/ARB, n (%)513 (55.16)135 (14.67)*
Data are presented as mean±SD or n(%). AF – atrial fibrillation; CHD – coronary heart disease; APOA1 – apolipoprotein A1; APOB – apolipoprotein B; Lp (a) – lipoprotein (a); TC – total cholesterol; TG – triglyceride; LDL-C – low-density lipoprotein cholesterol; HDL-C – high-density lipoprotein cholesterol; AST – aspartate aminotransferase; ALT – alanine aminotransferase; ALB – albumin; PAB – prealbumin; SCr – serum creatinine; SUA – serum uric acid.
* Statistically significant value (

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750