14 May 2022>: Clinical Research
Case-Control Study to Investigate the Association Between Serum Apolipoprotein B/A1 Ratio and Atrial Fibrillation by Sex in 920 Patients from China
Xia Zhong 1ACE , Huachen Jiao 2DFG* , Dongsheng Zhao 1BC , Jing Teng 1AF , Mengqi Yang 1BEDOI: 10.12659/MSM.936425
Med Sci Monit 2022; 28:e936425
Table 5 Subgroup analysis of the relationship between APOB/APOA1 ratio and metabolic factors in patients with atrial fibrillation.
Variable | Men (n=460) | Women (n=460) | ||||||
---|---|---|---|---|---|---|---|---|
≤0.61 | 0.61–0.83 | ≥0.83 | P value | ≤0.56 | 0.56–0.77 | ≥0.77 | P value | |
Number, n | 156 | 153 | 151 | 152 | 158 | 150 | ||
TG, mmol/L | 1.24±0.88 | 1.20±0.59 | 1.49±1.09 | * | 0.98±0.39 | 1.33±0.62 | 1.53±1.42 | |
TC, mmol/L | 4.19±1.09 | 4.15±0.89 | 4.47±1.13 | * | 3.78±0.80 | 4.46±1.01 | 4.87±1.19 | * |
LDL-C, mmol/L | 1.08±0.30 | 1.02±0.20 | 0.86±0.19 | * | 1.28±0.28 | 1.16±0.26 | 0.96±0.32 | * |
HDL-C, mmol/L | 2.50±0.89 | 2.56±0.71 | 2.87±0.79 | * | 1.96±0.53 | 2.68±0.92 | 3.17±0.88 | * |
APOA1, g/L | 1.13±0.26 | 1.10±0.21 | 0.92±0.21 | * | 1.32±0.24 | 1.24±0.22 | 1.01±0.25 | * |
APOB, g/L | 0.79±0.38 | 0.78±0.16 | 1.01±0.74 | * | 0.60±0.13 | 0.82±0.16 | 1.00±0.22 | * |
AST, U/L | 25.42±46.31 | 24.78±19.94 | 26.61±31.39 | 0.895 | 24.01±20.94 | 23.87±18.35 | 21.89±13.62 | 0.516 |
PAB, g/L | 19.55±5.92 | 21.38±5.62 | 18.83±7.45 | * | 19.39±5.00 | 20.19±5.39 | 17.90±5.82 | * |
ALB, g/L | 38.02±4.64 | 38.80±4.76 | 36.73±5.65 | * | 38.39±4.21 | 38.64±4.26 | 37.19±4.90 | * |
SCr, μmoI/L | 78.55±52.13 | 84.33±26.66 | 81.58±22.24 | 0.377 | 76.41±97.30 | 71.42±49.42 | 75.37±47.52 | 0.795 |
SUA,mg/dL | 5.89±1.76 | 6.14±1.69 | 6.32±2.09 | 0.957 | 5.48±1.42 | 5.71±1.44 | 5.94±1.83 | * |
Data are presented as mean±SD. TG – triglyceride; TC – total cholesterol; ALB – albumin; PAB – prealbumin; LDL-C – low-density lipoprotein cholesterol; HDL-C – high-density lipoprotein cholesterol; APOA1 – apolipoprotein A1; APOB – apolipoprotein B; AST – aspartate aminotransferase; PAB – prealbumin; ALB – albumin; SCr – serum creatinine; SUA – serum uric acid. * Statistically significant value ( |