20 May 2022 : Clinical Research
Importance of Influenza Anti-Hemagglutinin Antibodies During the SARS-CoV-2 Pandemic in the 2019/2020 Epidemic Season in Poland
Lidia B. Brydak1ADEFG, Karol Szymański1BF, Katarzyna Kondratiuk1BF, Anna Poznańska2CDE, Adam Kolondra1B, Ewelina Hallmann1BDEF*DOI: 10.12659/MSM.936495
Med Sci Monit 2022; 28:e936495
Table 3 Mean antibody level (GMT) for the analyzed virus strains and the response rate with 95% confidence intervals in the study subjects divided into vaccinated and unvaccinated against influenza in the 2019/2020 season; statistical significance of observed differences.
| Virus strain | Geometric mean titers GMT [95% CI] | Response rate [95% CI] | ||
|---|---|---|---|---|
| Vaccinated | Unvaccinated | Vaccinated | Unvaccinated | |
| A/Brisbane/02/2018 (H1N1)pdm09-like virus | 132.8 [122.2–153.4] | 81.2 [72.9–89.4] | 56.0% [50.0–62%] | 30.0% [26.5–33.6%] |
| p<0.001 | p<0.001 | |||
| A/Kansas/14/2017 (H3N2) -like virus | 123.7 [111.1–136.3] | 86.5 [81.0–92.0] | 72.9% [67.6–78.3%] | 60.4% [56.6–64.1%] |
| p<0.001 | p<0.001 | |||
| B/Colorado/06/2017 (B/Victoria lineage) -like virus | 80.4 [69.7–91.1] | 81.0 [72.4–89.7] | 48.9% [42.9–54.9%] | 25.4% [22.0–28.7%] |
| NS | p<0.001 | |||
| B/Phuket/3073/2013 (B/Yamagata lineage) -like virus | 87.9 [78.5–97.4] | 70.8 [66.2–75.4] | 77.1% [72.0–82.1%] | 55.4% [51.6–59.3%] |
| p=0.003 | p<0.001 | |||