Fully Automatic Knee Joint Segmentation and Quantitative Analysis for Osteoarthritis from Magnetic Resonance (MR) Images Using a Deep Learning Model

14 June 2022: Clinical Research

Xiongfeng Tang ^1ABCEF , Deming Guo ^1BF , Aie Liu ^2ACDE , Dijia Wu ^2ADE , Jianhua Liu ^3BCD , Nannan Xu ^3BDF , Yanguo Qin ^1ACDG*

DOI: 10.12659/MSM.936733

Med Sci Monit 2022; 28:e936733

Table 3 ICC and Spearman results of morphology analysis for the training and test sets.

Biomarkers		Training set				Test set
Biomarkers		MAD	ICC	R value	P value	MAD	ICC	R value	P value
Volume (mm)	FC	86.644	0.923	0.89		416.48	0.902	0.89
	LTC	97.886	0.955	0.927		56.855	0.913	0.927
	MTC	181.832	0.938	0.933		128.818	0.889	0.933
	LM	56.978	0.973	0.956		39.507	0.944	0.956
	MM	22.976	0.976	0.957		54.108	0.932	0.9857
Thickness (mm)	FC	0.041	0.88	0.806		0.117	0.832	0.806
	LTC	0.003	0.912	0.854		0.062	0.889	0.854
	MTC	0.059	0.91	0.858		0.131	0.841	0.858
	LM	0.041	0.96	0.908		0.081	0.899	0.908
	MM	0.036	0.959	0.927		0.139	0.918	0.927
JSW (mm)	L_JSW	0.367	0.895	0.813		0.224	0.889	0.813
JSW (mm)	M_JSW	0.275	0.871	0.818		0.144	0.909	0.818
Coverage (%)	L_Cov	0.06	0.93	0.861		5.1	0.873	0.861
Coverage (%)	M_Cov	0.02	0.941	0.892		5.7	0.856	0.892
MAD, mean absolute difference; ICC, intraclass correlation coefficient; ICC values 0.90 are indicative of poor, moderate, good, and excellent reliability, respectively. R value calculated by Spearman’s test; When value was less than 0.05, R value 0.8–1.0 was indicative of very strong correlation. FC – femoral cartilage; LM – lateral meniscus; MM – medial meniscus; LTC – lateral tibial cartilage; MTC – medial tibial cartilage; JSW – joint space width.