10 August 2022: Clinical Research
A Retrospective Study from a Single Center to Identify Hematological Factors that Distinguish Between Patients with Colorectal Carcinoma and Colorectal Adenoma
Jun Huang 12AE , Pingping Xu 3BCD , Youxiang Chen 4AE*DOI: 10.12659/MSM.936745
Med Sci Monit 2022; 28:e936745
Table 5 Diagnostic indicators for CRC patients using the multivariate logistic regression model in participants grouped into poorly differentiated CRC, moderately and well-differentiated CRC, and colorectal adenoma.
| Variables | Model | β | SE | Wald | P | OR | 95% CI | |
|---|---|---|---|---|---|---|---|---|
| Lower | Upper | |||||||
| PT | Colorectal adenoma & Poorly differentiated CRC | 0.6731 | 0.1365 | 24.3288 | 1.960 | 1.500 | 2.561 | |
| Colorectal adenoma & Moderately/well-differentiated CRC | 0.8786 | 0.1803 | 23.7555 | 2.408 | 1.691 | 3.428 | ||
| TT | Colorectal adenoma & Poorly differentiated CRC | 0.4253 | 0.0748 | 32.3168 | 1.530 | 1.321 | 1.772 | |
| Colorectal adenoma & Moderately/well-differentiated CRC | 0.5524 | 0.0980 | 31.7703 | 1.737 | 1.434 | 2.105 | ||
| A/G | Colorectal adenoma & Poorly differentiated CRC | 0.3245 | 0.0429 | 57.3282 | 1.383 | 1.272 | 1.504 | |
| Colorectal adenoma & Moderately/well-differentiated CRC | 0.3777 | 0.0602 | 39.3273 | 1.459 | 1.296 | 1.642 | ||
| PCT | Colorectal adenoma & Poorly differentiated CRC | 0.2225 | 0.0917 | 5.8865 | 0.015 | 1.249 | 1.044 | 1.495 |
| Colorectal adenoma & Moderately/well-differentiated CRC | 0.2493 | 0.1242 | 4.0306 | 0.045 | 1.283 | 1.006 | 1.637 | |
| FAR | Colorectal adenoma & Poorly differentiated CRC | 0.4039 | 0.0642 | 39.5489 | 1.498 | 1.321 | 1.699 | |
| Colorectal adenoma & Moderately/well-differentiated CRC | 0.5100 | 0.0820 | 38.6862 | 1.665 | 1.418 | 1.956 | ||
| HPR | Colorectal adenoma & Poorly differentiated CRC | −4.2277 | 0.9121 | 21.4845 | 0.015 | 0.002 | 0.087 | |
| Colorectal adenoma & Moderately/well-differentiated CRC | −3.9132 | 1.2829 | 9.3042 | 0.002 | 0.020 | 0.002 | 0.247 | |
| OR – odds ratio; CI – confidence interval; SE – standard error; β – beta coefficient; Wald – Wald Chi-square; PT – prothrombin time; TT – thrombin time; A/G – albumin-globulin ratio; PCT – plateletcrit (the product of platelet and mean platelet volume); FAR – fibrinogen-albumin ratio; HPR – hemoglobin-platelet ratio; CRC – colorectal cancer. | ||||||||