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10 August 2022: Clinical Research

A Retrospective Study from a Single Center to Identify Hematological Factors that Distinguish Between Patients with Colorectal Carcinoma and Colorectal Adenoma

Jun Huang 12AE , Pingping Xu 3BCD , Youxiang Chen 4AE*

DOI: 10.12659/MSM.936745

Med Sci Monit 2022; 28:e936745

Supplementary Table 1 Proportion of missing variables and sensitivity analysis.

CharacteristicData missing ratio (%)After interpolationBefore interpolationStatisticsP
Hb, g/L, Mean±SD0.12125.14±24.58125.15±24.59t=−0.0100.996
RBC, 10/L, Mean±SD0.124.21±0.654.21±0.65t=−0.0300.975
WBC, 10/L, M (Q, Q)0.125.87 (4.77, 7.34)5.87 (4.77, 7.34)Z=0.0340.973
NEUT, 10/L, M (Q, Q)0.123.67 (2.83, 5.15)3.67 (2.83, 5.15)Z=0.0330.974
LYM, 10/L, M (Q, Q)0.121.42 (1.07, 1.80)1.42 (1.07, 1.80)Z=0.0050.996
MONO, 10/L, M (Q, Q)0.120.35 (0.26, 0.46)0.35 (0.26, 0.46)Z=0.0320.975
PLT, 10/L, M (Q, Q)0.12227.00 (181.00, 281.00)227.00 (181.00, 281.00)Z=0.0360.971
MPV, fL, Mean±SD1.4010.14±1.4910.13±1.48t=0.1300.900
PCT, %, Mean±SD1.400.24±0.080.24±0.08t=−0.2000.840
RDW, %, Mean±SD0.1213.51±2.3913.51±2.39t=−0.0010.998
PT, s, Mean±SD1.1211.25±1.0111.26±1.01t=−0.0100.993
APTT, s, Mean±SD1.1226.76±4.1726.76±4.17t=−0.0010.996
TT, s, Mean±SD1.1218.31±1.7918.32±1.79t=−0.0800.934
FIB, g/L, Mean±SD1.123.07±0.843.07±0.83t=0.0300.973
D-dimer, mg/L, M (Q, Q)1.400.30 (0.17, 0.60)0.30 (0.17, 0.60)Z=0.0490.961
CEA, ng/mL, M (Q, Q)9.581.86 (0.90, 3.51)1.90 (0.91, 3.58)Z=0.3840.701
Carbohydrate antigen 199, U/mL, M (Q, Q)10.4010.94 (6.80, 19.42)11.11 (6.92, 19.62)Z=0.2790.780
Carbohydrate antigen 125, U/mL, M (Q, Q)24.538.50 (5.90, 12.65)8.50 (6.30, 12.60)Z=0.4690.639
GPT, U/L, M (Q, Q)0.5816.00 (11.30, 24.00)16.00 (11.60, 24.00)Z=0.0400.968
GOT, U/L, M (Q, Q)0.5821.00 (17.00, 26.00)21.00 (17.00, 26.00)Z=0.0160.987
TBil, μmol/L, M (Q, Q)0.5813.00 (9.25, 17.80)13.00 (9.20, 17.80)Z=−0.0350.972
ALB+GLB, g/L, Mean±SD0.5866.61±7.4866.62±7.49t=−0.0100.989
ALB, g/L, Mean±SD0.5841.63±4.9041.63±4.91t=−0.0300.977
GLB, g/L, Mean±SD0.5824.99±4.5624.99±4.56t=0.0100.994
A/G, Mean±SD0.581.71±0.331.71±0.33t=−0.0200.982
BUN, mmol/L, M (Q, Q)0.584.80 (3.80, 5.80)4.80 (3.80, 5.80)Z=0.0440.965
Cr, μmol/L, M (Q, Q)0.5871.00 (61.00, 84.00)71.00 (61.00, 84.00)Z=0.0140.988
UA, μmol/L, M (Q, Q)1.12288.00 (221.00, 359.00)288.00 (221.00, 359.00)Z=−0.0290.977
SD – standard deviation; M (Q1, Q3) – median (interquartile range); Hb – hemoglobin; RBC – red blood cell; WBC – white blood cell; NEUT – neutrophil; LYM – lymphocyte; MONO – monocyte; PLT – platelet; MPV – mean platelet volume; PCT – plateletcrit (the product of PLT and MPV); RDW – red blood cell distribution width; PT – prothrombin time; APTT – activated partial thromboplastin time; TT – thrombin time; FIB – fibrinogen; CEA – carcinoembryonic antigen; GPT – glutamic pyruvic transaminase; GOT – glutamic oxaloacetic transaminase; TBil – total bilirubin; ALB – albumin; GLB – globulin; A/G – ALB-to-GLB ratio; BUN – blood urea nitrogen; Cr – creatinine; UA – uric acid.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750