Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

27 July 2022: Meta-Analysis

The Prognostic Value of Periostin Expression in Non-Small Cell Lung Cancer: A Meta-Analysis

Mengjie Li 1234ABCDEFG* , Guangzhi Ma 1ABCDEF* , Xuebing Li 2ACFG* , Qinghua Zhou 12ACFG*

DOI: 10.12659/MSM.936898

Med Sci Monit 2022; 28:e936898

Table 1 Characteristics of the included articles.

AuthorCountryMedian ageN (F/M)Clinical stageMethodAntibodyHR estimationCut-offPeriostin (H/L)Quality score
Iwamoto 2021 []25 Japan6573 (34/39)I–IIIAIHCMMHR+ClScore ≥434/397
Ratajczak-Wielgomas 2020 []24 PolandNANAI–IVIHCRPHR+ClScore >7360/3408
Okazaki 2018 []19 JapanNA189 (83/106)I–IIIIHCRPHR+ClScore ≥283/1068
Murakami 2018 []18 Japan68184 (83/101)I–IIIIHCMMHR+ClScore >43265.592/928
Zhang 2017 []20 ChinaNA122 (34/88)III–IVELISAMMHR+Cl435.04 ng/mLNA7
Xu 2017 []21 China56.6296 (116/180)I–IVELISAkit* HR+Cl30.87 ng/mLNA7
Nitsche 2016 []26 GermanyNA93 (37/56)I–IVIHCRPHR+ClMedian value47/467
Hong 2013 []22 China57.13249 (11/38)I–IVWestern BlotRPHR+ClNA22/277
Takanami 2008 []27 Japan65.588 (25/63)I–IIIAIHCMMHR+ClScore ≥+37/518
Soltermann 2008 []28 Switzerl-andNA516 (149/367)I–IVIHCRPHR+ClScore >3160/3567
Sasaki 2001 []23 Japan64.5102 (24/78)I–IVRT-PCRNASurvival curvesRatio >2.0# 50/527
Sasaki 2001 []16 Japan6392 (19/73)I–IIIBChemilum-inescence5H8, E17** Survival curves962 ng/mL46/467
CI – confidence interval; F – female; H – high; HR – hazard ratio; IHC – immunohistochemistry; L – low; M – male; MM – mouse monoclonal anti-periostin antibody; MVD – microvessel density; N – number of patients; NA – not available; RP – rabbit polyclonal anti-periostin antibody;
* kit – commercial periostin ELISA Ready-SET-Go kit;
** 5H8=monoclonal antibody and E17=polyclonal antibody;
# ratio – tumor/normal ratio.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750