12 August 2022 : Clinical Research
Clinical Value of Metagenomic Next-Generation Sequencing in Immunocompromised Patients with Sepsis
Zheng Cheng1ABCDEFG, Feng Yu1ABCDEFG*DOI: 10.12659/MSM.937041
Med Sci Monit 2022; 28:e937041
Table 2 Difference of pathogenic spectrum between ICO and ICH.
| Species | ICO (60) | ICH (30) | P value | Rate difference (95% CI) |
|---|---|---|---|---|
| 20 | 9 | 0.75 | 0.03 (0–0.23) | |
| 20 | 8 | 0.52 | 0.06 (0–0.26) | |
| 15 | 3 | 0.094 | 0.15 (0–0.30) | |
| 12 | 6 | 1 | 0.00 (0–0.17) | |
| 12 | 3 | 0.23 | 0.10 (0–0.24) | |
| 7 | 4 | 1 | 0.01 (0–0.16) | |
| 4 | 1 | 0.871 | 0.03 (0–0.12) | |
| 4 | 1 | 0.871 | 0.03 (0–0.12) | |
| 2 | 3 | 0.416 | 0.06 (0–0.18) | |
| 0 | 1 | NA | NA | |
| 2 | 0 | NA | 0.03 (0–0.07) | |
| 2 | 0 | NA | 0.03 (0–0.07) | |
| 4 | 1 | 0.871 | 0.03 (0–0.12) | |
| 0 | 1 | NA | NA | |
| 4 | 0 | NA | 0.06 (0–0.12) | |
| 1 | 9 | <0.001 | 0.28 (0.11–0.45) | |
| 12 | 6 | 1 | 0.00 (0–0.17) | |
| 3 | 1 | 1 | 0.01 (0–0.10) | |
| 3 | 1 | 1 | 0.01 (0–0.10) | |
| 2 | 3 | 0.416 | 0.06 (0–0.18) | |
| 1 | 0 | NA | 0.01 (0–0.04) | |
| 1 | 2 | 0.533 | 0.05 (0–0.14) | |
| CMV (cytomegalovirus) | 9 | 11 | 0.020 | 0.21 (0.02–0.41) |
| 4 | 0 | NA | 0.06 (0–0.12) | |
| CI – confidence interval; ICH – immunocompromised; ICO – immunocompetent; NA – not applicable. | ||||